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. 2017 May 2;7(5):e1112. doi: 10.1038/tp.2017.62

Table 7. The association between elevated hsCRP and herpes antibody levels at age 16 and the presence of any mood and any anxiety disorders at age 19.

  Any mood disorder
Any anxiety disorder
  OR 95% CI B s.e. P OR 95% CI B s.e. P
hsCRP>2 mg/l
 Unadjusted 0.92 0.50–1.66 -0.10 0.30 0.773 1.46 0.76–2.80 0.38 0.33 0.251
 Demographicsa 1.04 0.57–1.92 0.04 0.31 0.894 1.70 0.85–3.40 0.53 0.36 0.136
 Health behaviorsb 1.19 0.61–2.30 0.17 0.34 0.613 1.68 0.86–3.26 0.52 0.34 0.129
 
HSV1
 Unadjusted 0.85 0.48–1.53 -0.16 0.30 0.589 1.07 0.61–1.87 0.07 0.29 0.816
 Demographicsa 0.98 0.51–1.86 -0.02 0.33 0.946 1.32 0.71–2.47 0.28 0.32 0.377
 Health behaviorsb 1.06 0.55–2.02 0.05 0.33 0.870 1.21 0.64–2.30 0.19 0.33 0.551
 
EBV
 Unadjusted 1.32 0.37–4.65 0.28 0.64 0.667 0.65 0.11–3.82 −0.43 0.91 0.632
 Demographicsa 1.33 0.36–4.98 0.29 0.67 0.669 0.60 0.10–3.73 −0.50 0.93 0.587
 Health behaviorsb 1.11 0.27–4.55 0.11 0.72 0.882 0.62 0.10–3.79 −0.48 0.93 0.602
 
CMV
 Unadjusted 0.58 0.26–1.27 −0.55 0.40 0.172 0.94 0.49–1.80 −0.07 0.34 0.842
 Demographicsa 0.52 0.22–1.22 −0.65 0.43 0.131 0.88 0.44–1.77 −0.12 0.36 0.728
 Health behaviorsb 0.63 0.28–1.43 −0.47 0.42 0.268 0.83 0.40–1.75 −0.18 0.38 0.630

Abbreviations: BMI, body mass index; CI, confidence interval; CMV, cytomegalovirus antibody levels in the seropositive group (N=266); EBV, Epstein–Barr virus antibody levels in the seropositive group (N=263); hsCRP, high-sensitive C-reactive protein tested in the whole sample (N=1084); HSV1, herpes simplex virus type 1 antibody levels in the seropositive group (N=258); SES, socioeconomic status.

a

Adjusted for sex, ethnicity, SES and lifetime diagnosis.

b

Adjusted for sex, ethnicity, SES, lifetime diagnosis, BMI, nicotine use and alcohol use.

HHS Vulnerability Disclosure