Table 7. The association between elevated hsCRP and herpes antibody levels at age 16 and the presence of any mood and any anxiety disorders at age 19.
Any mood disorder |
Any anxiety disorder |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | B | s.e. | P | OR | 95% CI | B | s.e. | P | |
hsCRP>2 mg/l | ||||||||||
Unadjusted | 0.92 | 0.50–1.66 | -0.10 | 0.30 | 0.773 | 1.46 | 0.76–2.80 | 0.38 | 0.33 | 0.251 |
Demographicsa | 1.04 | 0.57–1.92 | 0.04 | 0.31 | 0.894 | 1.70 | 0.85–3.40 | 0.53 | 0.36 | 0.136 |
Health behaviorsb | 1.19 | 0.61–2.30 | 0.17 | 0.34 | 0.613 | 1.68 | 0.86–3.26 | 0.52 | 0.34 | 0.129 |
HSV1 | ||||||||||
Unadjusted | 0.85 | 0.48–1.53 | -0.16 | 0.30 | 0.589 | 1.07 | 0.61–1.87 | 0.07 | 0.29 | 0.816 |
Demographicsa | 0.98 | 0.51–1.86 | -0.02 | 0.33 | 0.946 | 1.32 | 0.71–2.47 | 0.28 | 0.32 | 0.377 |
Health behaviorsb | 1.06 | 0.55–2.02 | 0.05 | 0.33 | 0.870 | 1.21 | 0.64–2.30 | 0.19 | 0.33 | 0.551 |
EBV | ||||||||||
Unadjusted | 1.32 | 0.37–4.65 | 0.28 | 0.64 | 0.667 | 0.65 | 0.11–3.82 | −0.43 | 0.91 | 0.632 |
Demographicsa | 1.33 | 0.36–4.98 | 0.29 | 0.67 | 0.669 | 0.60 | 0.10–3.73 | −0.50 | 0.93 | 0.587 |
Health behaviorsb | 1.11 | 0.27–4.55 | 0.11 | 0.72 | 0.882 | 0.62 | 0.10–3.79 | −0.48 | 0.93 | 0.602 |
CMV | ||||||||||
Unadjusted | 0.58 | 0.26–1.27 | −0.55 | 0.40 | 0.172 | 0.94 | 0.49–1.80 | −0.07 | 0.34 | 0.842 |
Demographicsa | 0.52 | 0.22–1.22 | −0.65 | 0.43 | 0.131 | 0.88 | 0.44–1.77 | −0.12 | 0.36 | 0.728 |
Health behaviorsb | 0.63 | 0.28–1.43 | −0.47 | 0.42 | 0.268 | 0.83 | 0.40–1.75 | −0.18 | 0.38 | 0.630 |
Abbreviations: BMI, body mass index; CI, confidence interval; CMV, cytomegalovirus antibody levels in the seropositive group (N=266); EBV, Epstein–Barr virus antibody levels in the seropositive group (N=263); hsCRP, high-sensitive C-reactive protein tested in the whole sample (N=1084); HSV1, herpes simplex virus type 1 antibody levels in the seropositive group (N=258); SES, socioeconomic status.
Adjusted for sex, ethnicity, SES and lifetime diagnosis.
Adjusted for sex, ethnicity, SES, lifetime diagnosis, BMI, nicotine use and alcohol use.