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Partial least square-discriminant analysis (PLS-DA) modeling of ultraperformance liquid chromatography–mass spectrometry (UPLC–MS/MS) spectral data derived from aqueous extracts of prefrontal cortex samples in the positive ion mode. (a) All seven groups; (b) atypical antipsychotic drug (AAPD) groups versus normal control (NC). ARI, aripiprazole; CLO, clozapine; CUMS, chronic unpredictable mild stress; LTDE, long-term dexamethasone exposure; RIS, risperidone.
