Figure 2.
Levels of proBDNF, mature BDNF and BDNF pro-peptide in human brain regions derived from control, MDD, SZ and BD groups. Western blot analysis was performed on proBDNF, mature BDNF, BDNF pro-peptide and β-actin in the parietal cortex and cerebellum of control (n=15), MDD (n=15), SZ (n=15) and BD (n=15) groups. The data are expressed as a percentage of control group values. The data are shown as mean±s.d. *P<0.05, **P<0.01, ***P<0.001 compared with the control group. BD, bipolar disorder; BDNF, brain-derived neurotrophic factor; MDD, major depressive disorder; NS, not significant; SZ, schizophrenia.