Table 1. Characteristics of the postmortem samples from Neuropathology Consortium of the Stanley Medical Research Institute.
| Characteristics | Control (n=15) | MDD (n=15) | SZ (n=15) | BD (n=15) | P-value |
|---|---|---|---|---|---|
| Age at death (years) | 48.1±10.7 (29–68) | 46.5±9.3 (30–65) | 44.5±13.1 (25–62) | 42.3±11.7 (25–61) | 0.540a |
| Gender (male/female) | 9/6 | 9/6 | 9/6 | 9/6 | |
| PMI (h) | 23.7±9.95 | 27.5±10.7 | 33.7±14.6 | 32.5±16.1 | 0.147a |
| Brain pH | 6.27±0.24 | 6.18±0.21 | 6.16±0.26 | 6.18±0.23 | 0.616a |
| Brain hemispheres (right/left) | 7/8 | 6/9 | 6/9 | 8/7 | 0.864b |
| Brain weight (g) | 1501.0±164.1 | 1462.0±142.1 | 1471.7±108.2 | 1441.2±171.5 | 0.740a |
| Storage days | 338.2±234.2 | 434.0±290.0 | 621.1±233.1 | 620.5±172.3 | 0.003a |
| Age of onset (years) | 33.9±13.3 | 23.2±8.0 | 21.5±8.4 | 0.003a | |
| Duration of disease (years) | 12.7±11.1 | 21.3±11.4 | 20.1±9.7 | 0.068a | |
| History of psychosis | 15 | 11 with (4 without) | 0.100c | ||
| Fluphenazine equivalent (mg) | 52267±62062 (1 never) | 20827±24016 (3 never) | 0.084d |
Abbreviations: BD, bipolar disorder; MDD, major depressive disorder; PMI, postmortem interval; SZ, schizophrenia.
a
One-way analysis of variance.
b
χ2 test for independence.
c
Fisher’s exact probability test.
d
Unpaired t-test.
The data are shown as the mean±s.d.