Table 2. Baseline characteristics and clinical data of the study population (separated by sleep-related- and non-sleep-related stroke onset).
| SIS (n = 19) | Non-SIS (n = 37) | p value | |
|---|---|---|---|
| Demographics | |||
| Mean age ± SD, years | 65.8 ± 7.0 | 63.6 ± 8.1 | 0.304 |
| Gender, male, n (%) | 5 (26) | 21 (57) | 0.031 |
| Risk factors | |||
| Hypertension, n (%) | 17 (89) | 32 (88) | 0.749 |
| Diabetes, n (%) | 6 (32) | 12 (32) | 0.948 |
| Dyslipidemia, n (%) | 9 (47) | 24 (41) | 0.208 |
| Smoking (past 5 years), n (%) | 2 (11) | 10 (65) | 0.154 |
| Coronary artery disease, n (%) | 1 (5) | 3 (8) | 0.696 |
| Atrial fibrillation, n (%) | 6 (32) | 2 (5) | 0.008 |
| Previous ischemic stroke/TIA, n (%) | 4 (21) | 16 (43) | 0.183 |
| Alcohol daily, n (%) | 2 (11) | 5 (13.5) | 0.749 |
| Clinical Data | |||
| Mean BMI ± SD | 27.5 ± 2.9 | 27.0 ± 4.4 | 0.706 |
| Median ESS, range | 5 (0–13) | 5 (0–11) | 0.701 |
| Median NIHSS, range | 1 (0–15) | 1 (0–7) | 0.177 |
| Stroke Severity | 0.078* | ||
| TIA, n (%) | 1 (5) | 9 (24) | |
| Minor stroke, n (%) | 16 (84) | 25 (68) | |
| Major stroke, n (%) | 2 (11) | 3 (8) | |
| TOAST | 0.051* | ||
| Large artery, n (%) | 10 (53) | 24 (65) | |
| Cardioembolism, n (%) | 7 (37) | 3 (8) | |
| Small vessel, n (%) | 1 (5) | 6 (16) | |
| Other, n (%) | 0 | 0 | |
| Undetermined, n (%) | 1 (5) | 4 (11) | |
| Sleep apnea, n (%) | 18 (95) | 33 (89) | 0.801* |
| Mild | 5 (26) | 13 (35) | |
| Moderate | 7 (37) | 10 (27) | |
| Severe | 6 (32) | 10 (27) | |
SIS sleep-related ischemic stroke, TIA transient ischemic attack, BMI body mass index, ESS Epworth Sleepiness Scale, NIHSS National Institutes of Health Stroke Scale, TOAST Trial of Org 10172 in Acute Stroke Treatment
*
Overall p value for all categories