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Transactivation of CAR (a) and PXR (b) in HepG2 and HEK-T cells. The cells were transfected with plasmids before incubation with PTX-2 for 24 h. CITCO (10 μM) and SR12813 (10 μM) were used as positive controls. The results were obtained from three independent experiments performed in triplicate (mean ± SD). *** p < 0.001 after one-way ANOVA followed by Dunnett’s post hoc tests.
