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The plasma concentrations of IS following acute administration. VEH—control group; IS—indoxyl sulfate; ** p < 0.01 compared to control; *** p < 0.001 compared to control; ^ p < 0.05 compared to 3 mg/kg body weight (b.w.) of IS; ^^^ p < 0.001 compared to 3 mg/kg b.w. of IS; && p < 0.01 compared to 10 mg/kg b.w. of IS.
