Table 4.

Main and sensitivity analyses of benefit-harm metrics at different time points after randomization

		Benefit-harm metric	95% confidence interval*	Probability of the metric being positive*
Main analysis
6 months		−129	−242 to −14	1%
12 months		−317	−436 to −196	0%
18 months		−390	−514 to −264	0%
24 months		−526	−687 to −368	0%
Sensitivity analysis one
6 months		−201	−362 to −39	1%
12 months		−482	−665 to −298	0%
18 months		−603	−800 to −412	0%
24 months		−808	−1049 to −570	0%
Sensitivity analysis two
6 months		−115	−245 to 13	4%
12 months		−292	−421 to −161	0%
18 months		−339	−467 to −209	0%
24 months		−439	−588 to −294	0%

^*95% confidence interval and the probability of the metric being positive were calculated based on the 10000 bootstrapping replicates.