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. 2017 Jul 31;4:50. doi: 10.3389/fcvm.2017.00050

Table 1.

Study phenotype criteria.

Study phenotype Criteria
Troponin (ng/ml) Histology Presentation Blinded angiographic assessment
Stable CAD (n = 15) Ortho VITROS 5600 Assay: “Peak” troponin level < 0.035
Beckman Access “Peak” troponin level < 0.04		 Elective coronary angiogram
History of CVD: CABG, PCI, CVA/TIA, CEA, PAD, or AAA procedure or angiographic criteria		 Satisfies ALL criteria below:

  1. >50% stenosis in one or greater epicardial vessel (only required if no history of CVD)

  2. TIMI flow = 3 (all vessels)

  3. TIMI MPG = 3 (all vessels)
Acute MI (n = 49) Ortho VITROS 5600 Assay: “Peak” troponin level > 0.12
Beckman Access “Peak” troponin level > 0.5		 Non-elective coronary angiogram
Clinical presentation consistent with WHF/ECC/ACC/AHA Universal definition of AMI
Thrombotic MI (n = 22) Ortho VITROS 5600 Assay: “Peak” troponin level > 0.12
Beckman Access “Peak” troponin level >0.5 and >30% increase in troponin from T0 to T6		 Histologically confirmed coronary thrombus 0–4 days old by blinded pathological assessment Non-elective coronary angiogram
Clinical presentation consistent with WHF/ECC/ACC/AHA Universal definition of AMI		 Stenosis in the vessel in which thrombus was recovered of 50–100% and ST elevation in territory supplied by the vessel in which thrombus was recovered
Non-thrombotic MI (n = 12) Ortho VITROS 5600 Assay: “Peak” troponin level >0.12
Beckman Access “Peak” troponin level >0.5		 No histologically confirmed thrombus recovered Clinical presentation consistent with WHF/ECC/ACC/AHA Universal definition of AMI Satisfies ALL 5 criteria below, in all vessels:

  1. <50% stenosis

  2. No filling defect

  3. Simple Ambrose lesion morphology

  4. TIMI flow = 3

  5. TIMI MPG = 3

CAD, coronary artery disease; MI, myocardial infarction; TIMI, thrombolysis in myocardial infarction; MPG, myocardial perfusion grade; CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention; CVA, cerebral vascular accident; TIA, transient ischemic attack; CEA, carotid endarterectomy; PAD, peripheral artery disease; AAA, abdominal aortic aneurysm; CVD, cardiovascular disease.