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. Author manuscript; available in PMC: 2018 May 8.
Published in final edited form as: Int J Toxicol. 2017 May 8;36(3):199–206. doi: 10.1177/1091581817706067

Figure 4.

Figure 4

Increased β-catenin activation in ESR1-KO livers after CCl4 treatment. (A) Western blot analysis of total and activated β-catenin, phosphorylated nuclear p65; and total and phosphorylated GSK3β proteins at 12, 24 and 48 hr after CCl4 treatment performed using total liver cell extracts of WT and ESR1-KO rat livers. (B) Bar graphs showing densitometric analysis of the active β-catenin western blot. (C) Bar graphs showing densitometric analysis of the phosphorylated GSK3β western blot. * denotes significant difference at P≤0.05 between WT and KO.