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. 2017 Jun 24;18(7):1356. doi: 10.3390/ijms18071356

Figure 1.

Figure 1

miR-210 exacerbates cerebral edema and serum immunoglobulin G (IgG) leakage after neonatal hypoxic-ischemic (HI) insult. Pups received either miR-210 mimic or its negative control (Neg. Ctrl) via intracerebroventricular injection (i.c.v.) injection 48 h prior to HI insult (1.5 h of hypoxia, 8% O2). Cerebral edema (A) was determined 48 h following HI based on the infarct volume assay, and serum IgG extravasation into the brain tissue (B) was determined 24 h following HI by western blotting. n = 6–8. * p < 0.05, miR-210 vs. Neg. Ctrl.