Table 2.
Common cumulative toxicities reported in patients after folinic acid/5-fluorouracil/oxaliplatin (FOLFOX4) treatment.
| Toxicity Type | Patients with G3-4 Events (n = 144) | |
|---|---|---|
| n | % | |
| Hematological | 55 | 38.2 |
| Anemia | 0 | 0.0 |
| Fever with severe neutropenia | 2 | 1.4 |
| Leucopenia | 7 | 4.9 |
| Neutropenia | 53 | 36.8 |
| Thrombocytopenia | 1 | 0.7 |
| Non-Hematological | 27 | 18.8 |
| Alopecia | 0 | 0.0 |
| Asthenia | 0 | 0.0 |
| Cardiac | 1 | 0.7 |
| Constipation | 1 | 0.7 |
| Diarrhea | 16 | 11.1 |
| Hepatic (hyperbilirubinemia) | 1 | 0.7 |
| Infection without severe neutropenia | 0 | 0.0 |
| Mucositis | 2 | 1.4 |
| Nausea | 3 | 2.1 |
| Vomiting | 5 | 3.5 |
| Neurotoxicity | 10 | 6.9 |