Table 3.

Summary of the results obtained from CoMFA (comparative molecular field analysis) and CoMSIA (comparative molecular similarity index analysis) analyses.

Statistical Parameter	CoMFA Model	CoMSIA Model
q2	0.750	0.710
ONC	7	6
R2	0.993	0.975
SEE	0.042	0.080
F	383.856	124.834
R2pred	0.6465	0.931
Contribution
Steric	0.726	0.140
Electrostatic	0.274	0.334
Hydrophobic		0.239
H-bond donor		0.197
H-bond acceptor		0.090