Figure 1.

Algorithm for the initiation of renal replacement therapy (“Heidelberg Standard”) [74,75]. AKI, Acute kidney injury; BUN, Blood urea nitrogen; FO, Fluid overload; FiO₂, Fractional inspired oxygen; K⁺, Potassium; O₂, Oxygen; RRT, Renal replacement therapy. ^a Unexplained decline in mental status, nausea, vomiting, bleedings due to thrombocytophatia, pericarditis, pruritus. ^b RRT might be beneficial despite unstable hemodynamics, especially in cardiac decompensation or critical O₂ demand. An individual risk-benefit analysis is mandatory.