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Skeletal muscle atrophy. The graphs summarize: the gastrocnemius muscle weight, normalized to body weight, expressed in grams (A); and the Feret’s myotube diameter of gastrocnemius skeletal muscle, expressed in µm (B). ANOVA, two-way analysis of variance; * p ≤ 0.05 vs. Reserpine four days; # p ≤ 0.05 vs. Reserpine plus tap water; + p ≤ 0.05 vs. Reserpine plus melatonin 5 mg/kg/day for 2 months and ° p ≤ 0.05 vs. Controls. H2O: tap water; MEL: melatonin; Res: reserpine.
