Figure 6.

Skeletal muscle oxidative stress and constitutive markers quantitative analyses. The graphs summarize the histomorphometrical analyses expressed in arbitrary units (AU) of: superoxide dismutase 1 (SOD1) (A); catalase (CAT) (B); cyclooxygenase-1 (COX-1) (C); and sirtuin 3 (SIRT3) (D) immunopositivity at gastrocnemius skeletal muscle level. ANOVA, two-way analysis of variance; * p ≤ 0.05 vs. Reserpine four days; # p ≤ 0.05 vs. Reserpine plus tap water; + p ≤ 0.05 vs. Reserpine plus melatonin 5 mg/kg/day for 2 months and ° p ≤ 0.05 vs. Controls. H₂O: tap water; MEL: melatonin; Res: reserpine.