Table 1.
The names of the histone methylation-related factors mentioned in this paper and their synonyms.
| Symbol | Previous Symbol | Synonym(s) | Residue | Function |
|---|---|---|---|---|
| ASH1L | ASH1L | ASH1, ASH1L1, huASH1, KMT2H | H3K36 | Methyltransferase |
| DOT1L | DOT1L | DOT1, KIAA1814, KMT4 | H3K79 | Methyltransferase |
| EHMT1 | EHMT1 | bA188C12.1, Eu-HMTase1, FLJ12879, KIAA1876, KMT1D | H3K9 | Methyltransferase |
| EHMT2 | BAT8, C6orf30 | Em:AF134726.3, G9A, KMT1C, NG36/G9a | H3K9 | Methyltransferase |
| EZH1 | EZH1 | KIAA0388, KMT6B | H3K27 | Methyltransferase |
| EZH2 | EZH2 | ENX-1, EZH1, KMT6, KMT6A | H3K27 | Methyltransferase |
| KDM1A | AOF2, KDM1 | BHC110, KIAA0601, LSD1 | H3K4, H3K9, H4K20 | Demethylase |
| KDM2A | FBXL11, KDM2A | CXXC8, DKFZP434M1735, FBL11, FBL7, FLJ00115, JHDM1A, KIAA1004, LILINA | H3K36 | Demethylase |
| KDM2B | FBXL10, KDM2B | CXXC2, Fbl10, JHDM1B, PCCX2 | H3K36 | Demethylase |
| KDM3A | JMJD1, JMJD1A, KDM3A | JHMD2A, KIAA0742, TSGA | H3K9 | Demethylase |
| KDM3B | C5orf7, JMJD1B, KDM3B | KIAA1082, NET22 | H3K9 | Demethylase |
| KDM4A | JMJD2, JMJD2A, KDM4A | JHDM3A, KIAA0677, TDRD14A | H3K9, H3K36 | Demethylase |
| KDM4B | JMJD2B, KDM4B | KIAA0876, TDRD14B | H3K9, H3K36 | Demethylase |
| KDM4C | JMJD2C, KDM4C | GASC1, KIAA0780, TDRD14C | H3K9, H3K36 | Demethylase |
| KDM5A | JARID1A, KDM5A, RBBP2 | - | H3K4 | Demethylase |
| KDM5C | JARID1C, KDM5C, MRX13, SMCX | DXS1272E, XE169 | H3K4 | Demethylase |
| KDM6A | KDM6A, UTX | - | H3K27 | Demethylase |
| KDM6B | JMJD3, KDM6B | KIAA0346 | H3K27 | Demethylase |
| KMT2A | KMT2A, MLL | ALL-1, CXXC7, HRX, HTRX1, MLL1A, TRX1 | H3K4 | Methyltransferase |
| KMT2B | KMT2B | CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7 | H3K4 | Methyltransferase |
| KMT2C | KMT2C, MLL3 | HALR, KIAA1506 | H3K4 | Methyltransferase |
| KMT2D | KMT2D, MLL2, TNRC21 | ALR, CAGL114, MLL4 | H3K4 | Methyltransferase |
| KMT5A | KMT5A, SETD8 | PR-Set7, SET07, SET8 | H4K20 | Methyltransferase |
| KMT5B | KMT5B, SUV420H1 | CGI-85 | H4K20 | Methyltransferase |
| KMT5C | KMT5C, SUV420H2 | MGC2705 | H4K20 | Methyltransferase |
| NSD1 | STO | ARA267, FLJ22263, KMT3B | H3K36 | Methyltransferase |
| NSD2 | WHSC1 | KMT3G, MMSET | H3K36 | Methyltransferase |
| NSD3 | WHSC1L1 | FLJ20353, KMT3F, WHISTLE | H3K36 | Methyltransferase |
| ORC1 | ORC1L | HSORC1, PARC1 | H4K20 | Recognition |
| PHF2 | - | CENP-35, JHDM1E, KDM7C, KIAA0662 | H3K9, H4K20 | Demethylase |
| PHF8 | - | JHDM1F, KDM7B, KIAA1111, ZNF422 | H3K9, H4K20/H3K4 | Demethylase/Recognition |
| PHF21A | - | BHC80, BM-006, KIAA1696 | H3K4 | Recognition |
| RIOX1 | C14orf169 | FLJ21802, JMJD9, MAPJD, NO66 | H3K4, H3K36 | Demethylase |
| SETD1A | - | KIAA0339, KMT2F, Set1 | H3K4 | Methyltransferase |
| SETD1B | - | KIAA1076, KMT2G, Set1B | H3K4 | Methyltransferase |
| SETD2 | - | FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A | H3K36 | Methyltransferase |
| SETD3 | C14orf154 | FLJ23027 | H3K4, H3K36 | Methyltransferase |
| SETDB1 | SETDB1 | ESET, KG1T, KIAA0067, KMT1E, TDRD21 | H3K9 | Methyltransferase |
| SETMAR | - | Mentase | H3K4, H3K36 | Methyltransferase |
| SMYD2 | - | HSKM-B, KMT3C, ZMYND14 | H3K4, H3K36 | Methyltransferase |
| SUV39H1 | SUV39H | KMT1A | H3K9 | Methyltransferase |
| SUV39H2 | SUV39H2 | KMT1B FLJ23414 | H3K9 | Methyltransferase |
| UTY | UTY | KDM6AL, KDM6C | H3K27 | Demethylase |
| The names of the proteins are followed by HUGO Gene Nomenclature Committee (http://www.genenames.org/) | ||||