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. 2017 Jul 9;18(7):1471. doi: 10.3390/ijms18071471

Table 2.

List of potentially relevant, validated target genes for miRNAs regulated by R. rickettsia.

miRNAs Validated Target Genes (miRTarBase and DIANA-TarBase)
miR-129-5p CAMTA1, SOX4, NOTCH1, UBE2F, CDK6, BMPR2, GALNT1, FMR1
miR-200a-3p NOTCH1, CDK6, ZEB1, ZEB2, SMAD2, SMAD3, RIN2, VCAM1, KEAP1
miR-200b-3p ZEB1, ZEB2 SIP1, SMAD2, SMAD3, VEGFA, GATA4, KDR, XIAP, RIN2
miR-595 CALM1, TNIP2, PARD6A, ULK1, ACP1, SASH3, RAB10, HINT1
miR-548a-3p DSC2, FGF-7, CALM1, ILDR1, PRLR, TRIM13, PARP15, SOX4
miR-377-3p PAK1, SOD1, SOD2, SMAD5, PKD1, IGF2R, FKBP5, CARD8
miR-301b-3p OXA1L, FGFR1, SMAD4, LDLR, TGFBR2, SOX4, EDN1, SOD2