Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 12;18(7):1499. doi: 10.3390/ijms18071499

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Rhythmic expression of miRNAs identified in three breast cell lines. The heat maps depict the expression level of miRNAs over 28 h (hours 12–40 of the 48 h study) in (A) MCF-10A; (B) MCF-7; and (C) MDA-MB-231 cells. In addition, the heat maps show 6 different clusters of miRNAs that depict marked phases. Brown colors represent higher expression values, while yellow colors represent lower expression values. Expression values are z-scaled relative to each cell line; (D) Venn diagram of 143, 183, and 147 miRNAs that were rhythmically expressed over 28 h in MCF-10A, MCF-7, and MDA-MB-231. The diagram also shows miRNAs that exhibited rhythmicity across cell lines and were selected for RT-qPCR validation (red).

Rhythmic expression of miRNAs identified in three breast cell lines. The heat maps depict the expression level of miRNAs over 28 h (hours 12–40 of the 48 h study) in (A) MCF-10A; (B) MCF-7; and (C) MDA-MB-231 cells. In addition, the heat maps show 6 different clusters of miRNAs that depict marked phases. Brown colors represent higher expression values, while yellow colors represent lower expression values. Expression values are z-scaled relative to each cell line; (D) Venn diagram of 143, 183, and 147 miRNAs that were rhythmically expressed over 28 h in MCF-10A, MCF-7, and MDA-MB-231. The diagram also shows miRNAs that exhibited rhythmicity across cell lines and were selected for RT-qPCR validation (red).