Figure 1.

Processes affected by different microRNAs (miRNAs) that were found to be dysregulated in patients with bladder cancer. Cancer cells are subjected to different molecular mechanisms in order to proliferate and invade secondary sites. The main hallmarks consist in survival and proliferation, development of new vascular networks and acquisition of invasive characteristics within epithelial to mesenchymal transition (EMT). All these processes are controlled by aberrantly expressed miRNAs, throughout the progression of tumor cells towards metastasis. In red are represented the upregulated microRNAs and in green those downregulated in bladder cancer; the arrow represents promotion of a process, and the T bar represents suppression of a process.