Figure 1.

Proportional distribution of JRL domain containing proteins by superfamilies, among different kingdoms and taxa. JRL proteins (PF01419) of different taxonomic groups (bacteria, oomycetes, fungi, eudicotyledons, Liliopsida (monocotyledons) and other plants) were identified using UniProt. Domains were identified using NCBI Batch Web CD-Search Tool. Results were filtered for superfamilies as depicted. Below each pie chart the total number of JRL proteins that were found in the corresponding taxonomic group is given. Number next to the respective pie segment represent percentage of JRL domain containing proteins in depicted superfamily. Since chimeric JRL proteins may contain more than one partner domain, the respective protein might occur in different superfamilies, increasing the total percentage to >100. CRA: CT11-RanBPM; CTLH: C-terminal to LisH motif, alpha-helical motif of unknown function; DUF2235: domain of unknown function 2235; EEP: Exonuclease-Endonuclease-Phosphatase; ETX/MTX2: Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2; FBA_1: F-box associated 1; FU: Furin-like repeats; HHH_5: Helix-hairpin-helix domain; LisH: type-1-like homology motif; LRR_4: Leucin-rich repeats (2 copies); MACPF: Membrane-attack complex/Perforin domain; NPP1: necrosis-inducing protein; NUDE_C: NUDE protein, C-terminal conserved region; PI-PLCc_GDPD_SF: Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases; PKc: Protein Kinases, catalytic domain; P-loop_NTPase: P-loop containing Nucleoside triphosphate hydrolases; PolY: Y-family of DNA-Polymerases; PPR: PPR repeat, unknown function; RICIN: Ricin-type beta trefoil; RX-CC: coiled-coil domain of the potato virus X resistance protein and similar proteins; ZnMc: Zinc-dependent metalloproteases.