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Dexamethasone (Dexa) fails to induce antimycobacterial activity in human macrophages. MDMs were infected with BCG for 3–4 h before stimulation with Dexa (100 nM), IFN-γ, both in combination, or media alone for 3 d. Viable bacteria were quantified by CFU assay on day 3. Percentage antimicrobial activity relative to media (left panel) and CFU counts (right panel) are shown. Each colored row represents data obtained with MDMs from one individual donor (n = 3).
