Table 2.
Matrix metalloproteinases: MMP-2, MMP-3, MMP-9, and MMP-13 levels in maternal serum samples in both preeclamptic groups of women and in healthy controls.
| MMP-2 (ng/mL) | MMP-3 (ng/mL) | MMP-9 (ng/mL) | MMP-13 (ng/mL) | |
|---|---|---|---|---|
| The control group (n = 65) | 195.30 ± 43.53 Median 189.95 (103.88–347.83) |
29.23 ± 58.79 Median 16.749 (2.046–454.53) |
1752.59 ± 901.54 Median 1605.75 (336.83–4569.2) |
0.427 ± 0.228 Median 0.409 (0.014–1.047) |
| Statistical analysis, control-earlyPre | p = 0.000055∗ | p = 0.024386∗ | p = 0.063965 | p = 0.093083 |
| The group earlyPre (n = 29) | 242.93 ± 68.64 Median 235.26 (136.88–466.90) |
63.54 ± 71.58 Median 37.115 (13.65–314.14) |
1450.12 ± 838.01 Median 1153.32 (243.68–3383.13) |
0.590 ± 0.681 Median 0.407 (0.054–4.351) |
| Statistical analysis, earlyPre-latePre | p = 0.611400 | p = 0.011567∗ | p = 0.997154 | p = 0.364301 |
| The group latePre (n = 31) | 234.39 ± 79.18 Median 219.17 (124.19–514.79) |
27.91 ± 24.99 Median 18.04 (4.16–124.17) |
1450.86 ± 1165.93 Median 1040.2 (325.07–6430.0) |
0.482 ± 0.278 Median 0.385 (0.008–1,264) |
| Statistical analysis, control-latePre | p = 0.002550∗ | p = 0.995279 | p = 0.103238 | p = 0.295140 |
Data presented as a mean ± SD. ∗Statistical significance (p < 0.05); groups of studied pregnant women: control group: healthy normotensive pregnant women; earlyPre group: patients with pregnancy complicated by early-onset severe preeclampsia; latePre group: women with pregnancy complicated by late-onset severe preeclampsia.