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. 2017 Jul 17;2017:8647919. doi: 10.1155/2017/8647919

Table 3.

An enumeration of plant species that have been documented in literature to contain compounds and/or active ingredients that have effects on livestock ticks worldwide.

Species name of plant (English name) Family name of plant Part(s) of plant used Application form/action (effects) and target tick species Place Source/
Reference
Acalypha fruticosa Forssk. Var. Villosa Hutch Euphorbiaceae (spurge family) Leaf Sediment smeared onto the ears as repellent against ticks by the Turkana people of Kenya (aqueous preparation) eteteleit (Turkana language) Kenya [67]
As tick attractant as observed in the field and laboratory (Luo, Abaki) Kenya [122]

Acorus calamus L. Araceae (arum/ginseng family) Rhizome Repellent (aqueous and alcohol extracts) against Ixodes spp. USA [18, 123, 124]

Allium sativum (Link.) Döll. (Garlic) Alliaceae (onion family) Leaf/bulb Eat garlic pills, tick repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]

Ageratum houstonianum P. Mill. (Blue Mink) Compositae/Asteraceae (daisy/aster family) Essential oil from flowers Toxic to ticks (Rhipicephalus lunulatus) at LD50 = 0.06653 µl/cm2 within 24 hrs. Cameroon [126]

Aloe broomii Schonl. Xanthorrhoeaceae Leaf Boiling in water to make cattle dip and disinfectant. Oral leaf juice is made for cattle or for topical application South Africa; Kenya [67, 127]

Aloe ferox Mill. (cape aloe, bitter aloe, red aloe, and tap aloe) Xanthorrhoeaceae Leaf Infusion had a strong dipping and topical toxicity effect against Rhipicephalus appendiculatus ticks South Africa [128]

Aloe marlothii Alwin Berger (mountain aloe or the flat-flowered aloe) Xanthorrhoeaceae Leaf Dichloromethane extracts were repellent to Rhipicephalus appendiculatus South Africa [128]

Aloe spp. Xanthorrhoeaceae Leaf Topical application of a paste of leaves, paraffin oil, and kitchen ash Kenya [67]

Aloe secundiflora Engl. (aloe) Xanthorrhoeaceae Whole plant A concoction mixed with labia plant (Psiadia punctulata) to make an effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species) Kenya (Samburu pastoralists) in Baragoi [129]

Andropogon gayanus Kunth (bluestem, gamba, or llanero grass) Poaceae or Gramineae (the grass family) Whole plant Toxic/repellent South America, Mexico, Colombia [108, 130134]

Annona squamosa L. (sugar apple, custard apple, and sweetsop) Annonaceae (custard apple family) Leaf Leaves rubbed over floors or placed in hens' nests to keep away vermin which includes ticks India and Mexico [135]

Artocarpus altilis (Parkinson) Fosberg (breadfruit) Moraceae (fig/mulberry family) Fresh leaf Topical application of crude ethanol extracts/being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58, 136, 137]

Asclepias curassavica L. (redhead) Asclepiadaceae (milkweed family) Fresh leaf Topical application of crude ethanol extracts/being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Artemisia absinthium L. (wormwood) Asteraceae Whole plant Essential oils from the plant have been shown to have acaricidal activity Europe, Eastern North America [137] http://www.florahealth.com/about_int.cfm?sub_link=Export

Artemisia herba-alba Asso (white wormwood) Asteraceae Aerial parts Diethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844 Egypt [138]

Artemisia tridentata Nutt. (big sagebrush) Asteraceae Leaves Toxic to nymphal ticks (Ixodes scapularis (Say)) (LC50 = 0.180% wt : vol) USA [139]

Artemisia monosperma Del. (Tarragon) Asteraceae Aerial parts Diethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844. Essential oils showed toxicity effects to the larvae of H. dromedarii and Argas persicus Oken, 1818, adults Egypt [138]

Azadirachta indica Adr. Juss. (neem tree) Meliaceae (mahogany family) Whole plant; leaf; fruit Repellent/toxic/inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Kenya
Jamaica
[67, 140]
[58, 136]
Fruit Oil extracts caused mortality of Amblyomma variegatum larvae Nigeria [141]
Neem seed oil extracts caused mortality of Hyalomma anatolicum excavatum Koch larvae and malformation or deformities in developing ticks Egypt [142]
Neem oil and azadirachtin EC formulation At 2500 mg litre−1, azadirachtin caused significant reduction in feeding activity of larva (Hyalomma dromedarii), prolonged the period for molting to nymphal stage, and caused 60% reduction in moltability. Contact and dipping LC50 values were >40.7 µg cm−2 and >5000 mg litre−1, respectively. Saudi Arabia [143]
Seed Neem seed oil as an acaricide India [144]
Seed Neem seed oil as an acaricide against Boophilus microplus India [145, 146]
Seed Neem seed extracts as acaricide against Boophilus microplus Colombia [147]

Bixa orellana L. (annatto) Bixaceae (achiote/annatto/lipstick tree family) Fresh leaf Topical application of crude ethanol extracts/being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Jamaica [58]

Blighia sapida (ackee, akee, or achee) Sapindaceae (soapberry family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Jamaica [58]

Bocconia frutescens L. (tree celandine/parrotweed/plume
poppy)
Papaveraceae (poppy family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Jamaica [58]

Bontia daphnoides L. (kidney bush/white alling) Myoporaceae (Lamiales) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Jamaica [58]

Boscia angustifolia A. Rich Capparidaceae Aerial parts/oil Repellency of their essential oil Kenya [104]

Boscia mossambicensis Klotzsch Capparidaceae Aerial parts/oil Repellency of their essential oil Kenya [104]

Brachiaria brizantha (Hochst) Stapf cv. Marandu (marandu grass, surinam grass, signal grass, and Kenya sheep grass) Gramineae Whole plant Antitick properties South America, Brazil [131]

Brachiaria decumbens (signal grass) Grass family Panicoideae Whole plant Weak toxic/repellent South America [108]

Cadaba farinosa Forssk. Capparidaceae Aerial parts/oil Repellency of their essential oil Kenya [104]

Cadia purpurea (G. Piccioli) Aiton Caesalpiniaceae Whole plant A concoction mixed with Olea europaea subsp. Cuspidata (African olive tree) to make effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsii), Boophilus decoloratus, and bont tick (Amblyomma species) Kenya (Samburu pastoralists) in Baragoi [129]

Calocedrus decurrens (incense cedar and California post cedar) Cupressaceae (cypress family) Ground heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.343 and 0.015% wt : vol, resp.) USA [139]

Calotropis procera (Ait) R. Br. (rooster tree, giant milkweed, and sodom apple) Asclepiadaceae (milkweed family) A cardiac glycosidal (cardenolide) extract Contact and dipping LC50 values were 9.63 µg cm−2 and 1096 mg litre−1, respectively, against Hyalomma dromedarii larvae Saudi Arabia [143]
Latex Found to be acaricidal Egypt [148]

Calpurnia aurea Fabaceae/Papilionaceae/Leguminosae (Hardy annual legume/pea family) Leaf and bark Juice mixed with spice of Capsicum spp. Ethiopia [149]

Cinnamomum camphora (camphor plant) Lauraceae 
The Laurel family
Acaricide, essential oils repellent against Ixodes spp. USA [150]

Cannabis sativa L.(ganja/marijuana, marihuana, hemp, hashish, pot) Cannabaceae (hemp family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Capsicum annum L.(scotch bonnet/pimento or sweet pepper) Solanaceae (lemon pepper/nightshade/potato family) Fresh leaf Topical application of crude ethanol extracts. Being Toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Capsicum spp. Solanaceae (lemon pepper/nightshade/potato family) Fruits/leaves Spice mixed with juice of leaf and bark from Calpurnia aurea to form an acaricide Ethiopia [149]

Calpurnia aurea L. Fabaceae/Papilionaceae/Leguminosae/
Papilionaceae (hardy annual, legume/pea/bean family)
Leaf and bark Spice mixed with juice of leaf and bark from Calpurnia aurea to form an acaricide Ethiopia [149]

Carduus leptacanthus Fresen. Asteraceae (also known as Compositae or daisy family) Acaricide Rwanda [151]

Cassia tora L. Caesalpiniaceae/Leguminosae/
Papilionaceae/Fabaceae (hardy annual, legume bean/pea family)
Leaf Juice of smashed leaves orally India [152]

Cassia occidentalis L./Senna occidentalis L. (coffee senna/coffeeweed) Caesalpiniaceae/Leguminosae/
Papilionaceae/Fabaceae, (Hardy annual – legume Bean/pea Family)
Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition of Boophilus microplus Canst. Jamaica [58]

Catharanthus roseus L. (Madagascar periwinkle) Apocynaceae (dogbane family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Cecropia peltata L. (trumpet tree) Cecropiaceae (previously included in the family Moraceae, mulberry family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Cenchrus ciliaris L. (buffel grass) Poaceae (the grass family) Whole plant Repellent South America [113]

Chamaecyparis lawsoniana (A. Murr.) Parl. (Port Orford cedar) Cupressaceae (cypress family) Stump oil Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.487 and 0.041% wt : vol, resp.) USA [139]

Chamaecyparis nootkatensis (D. Don) Spach (Alaska yellow-cedar) Cupressaceae (cypress family) Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.151 and 0.007% wt : vol, resp.) USA [139]

Chebliswo-plant in Pokot vernacular in Kenya Root and Leaf Solution of smashed parts Kenya [153]

Chenopodium ambrosioides L. Mexican tea Chenopodiaceae (goose-foot family) Rwanda [151]

Chenopodium ugandae Chenopodiaceae (goose-foot family) Uganda [151]

Chrysanthemum cinerariaefolium L. Asteraceae (also known as Compositae or daisy family) Flowers Pyrethrins act as acaricide/toxicant/repellent USA [150]

Citronella plants Myrtaceae (Poaceae or Gramineae) Leaf Extracts-tick repellents against Ixodes spp. USA [154]

Citrullus lanatus Thunb. Cucurbitaceae (cucumber family) Fruit Zimbabwe [18, 105]

Citrus aurantium L.(Seville orange) Rutaceae (rue family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Cleome hirta (Klotzsch.) Oliv. Cleomaceae Aerial parts/oil Repellent/toxic/killer of ticks (Rhipicephalus appendiculatus) Kenya [155]

Cleome gynandra (Cleome) Cleomaceae Leaves Repellents and acaricides for certain larval, nymphal, and adult ticks South Africa http://www.daff.gov.za/docs/brochures/cleome.pdf

Clerodendrum glabrum E. Mey. Lamiaceae Leaf Acetone extracts showed relatively high repellency activity against Rhipicephalus appendiculatus ticks South Africa [128]

Commiphora swynnertonii Burtt. Burseraceae (copal family and/or torchwood family) Gum resin Repellency of their essential oil Kenya [104]

Commiphora erythraea Engler. Burseraceae (copal family and/or torchwood family) Gum resin/viscous oil/pure components/hexane extract Smear paste of camel urine and gum resin/toxic/repellent/larvicide Kenya [67, 116, 156, 157]

Commiphora holtziana Burseraceae (copal family and/or torchwood family) Gum, bark, and leaf Repellent Kenya [117]

Commiphora incisa Burseraceae (copal family and/or torchwood family) Gum resin Smear paste of camel urine and gum resin Kenya [67]

Commiphora merkeri Engl. Burseraceae (copal family and/or torchwood family) Gum, bark, and leaf Acaricide [158]

Commiphora myrrh Jacq. (Commiphora abyssinica (Nees) Engl., Commiphora myrrha (Nees) Engl., and Commiphora schimperi (Nees) Engl.) (all these plants are sources of Myrrh) Burseraceae (copal family and/or torchwood family) Gum resin/oil/pure components Toxic/Repellent Kenya [116, 156]
Oleoresin gum (crude myrrh) Myrrh essential oil/oil of Heerabol Myrrh (bola, myrrha and gum, common, and hirabol myrrh), repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]

Commiphora molmol Engler. Burseraceae (copal family and/or torchwood family) Myrrh LC50 of Myrrh extract caused death of fowl tick Argas persicus by destroying the epithelial gut of cells Egypt [159]

Commiphora tenuis Burseraceae (copal family) Larger leaf Toxic/repellent when rubbed on camels' coats Kenya Wanzala-Personal experience with Somali pastoralists

Crotalaria retusa L. (rattle weed) Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae, (Hardy annual, legume bean/pea family)
Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Cuscuta americana L. (love bush/weed) Cuscutaceae (Convolvulaceae) (dodder family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Cycloptis semicordata L. (tall fern) Polypodiaceae (polypody/fern family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Cymbopogon flexuosus (Nees ex Stend.) Wats. (lemon grass) Gramineae (Poaceae) (grass family) Leaf A blend with marjoram grass and tea tree essential oils forms antitick repellent spray New Zealand [160]

Cymbopogon martinii stapf var. motia/(Roxb.) Wats. var. motia Burk. Gramineae (Poaceae) (grass family)
Leaf/flower Palmarosa essential oil (Turkish Geranium/Andropogon/Nepal), tick repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]

Cymbopogon nardus R. (Andropogon nardus) (citronella grass, lemon grass, nardus) Gramineae (Poaceae) (grass family) Leaf/flower Citronella essential oil (lemon balm, Sri Lanka or Lenabatu citronella), tick repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]

Cynodon dactylon (star grass) Poaceae (grass family) Whole plant Weak toxic/repellent South America [108]

Datura stramonium L. Solanaceae (nightshade family) Seed/fruit Acaricide Rwanda [151]

Delphinium brunonianum Royle Ranunculaceae (Helleboraceae) (buttercup family) Leaf Juices of leaves used to destroy ticks USA [18, 161]

Derris elliptica (Sweet) Benth. Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Root powder Aqueous solution mixed with soft soap to make an acaricide USA [18, 150, 162164]

Digitalis purpurea L. (purple foxglove) Scrophulariaceae (Figwort family) A cardiac glycosidal (digitoxin) extract Contact and dipping LC50 values were 4.08 µg cm−2 and 409.9 mg litre−1, respectively, against Hyalomma dromedarii larvae Saudi Arabia [143]

Dioscorea polygonoides Willott (wild yam) Dioscoreaceae (yam family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Diplophyllum africanum Turcz. Scapaniaceae (Diplophyllaceae) Whole plant Acaricide Rwanda [151]

Dioscorea dumetorum (Kunth) Pax. Dioscoreaceae (yam family) Root Roots crushed in water to form a solution Tanzania [165, 166]

Dissotis throthae Melastomataceae (melastome family) Rwanda [151]

Ervatamia divaricate L. (Burkill.) (coffee rose) Apocynaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Erythrina corallodendron L. (Spanish maschette) Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae (hardy annual, legume bean/pea family)
Fresh leaf Topical application of crude ethanol extracts. Being Toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Eucalyptus spp. (gum trees) Myrtaceae (myrtle family) Leaf and branch Eucalyptus essential oil mixed with S. Nigra leaf extract make a repellent against Ixodes spp. USA [18, 167]

Eucalyptus spp. (gum trees) Myrtaceae (myrtle family) Leaf and branch Plant oil as an acaricide USA [167]

Eucalyptus spp. (gum trees) Myrtaceae (myrtle family) Leaf and branch Eucalyptus essential oil toxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol) USA [139]

Eucalyptus globulus Labill. (Tasmanian bluegum, eucalypt, and fever tree) Myrtaceae (myrtle family) Leaf and branch Eucalyptus essential oil, Tick repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]
Leaf Leaf decoction is traditionally used for repelling insects and vermin USA [168]

Eupatorium odoratum Penny Clifford (Chromolaena odorata (L.) RM King and H. Robinson) (Jack in the bush) Asteraceae (daisy/aster family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Eupatorium villosum (L.) George R. (bitter bush) Asteraceae (daisy/aster family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of embryogenesis of Boophilus microplus Canst. Jamaica [58]

Euphorbia aegyptiaca Boiss. Euphorbiaceae (spurge family) Aerial parts Diethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844 Egypt [138]

Euphorbia candelabrum Euphorbiaceae (spurge family) Latex Latex as toxic/killer/acaricide Kenya [140]

Euphorbia obovalifolia Euphorbiaceae (spurge family) Latex Acaricide Ethiopia [149]

Fagara microcarpa (Griseb.) Krug & Urb. (bitter bush) Rutaceae (citrus family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Ficus brachypoda Moraceae Latex Acaricide Ethiopia [149]

Ficus cfr. burkei Moraceae Acaricide Rwanda [151]

Foeniculum vulgare P. Mill. (Florence fennel, finocchio, anise, and sweet fennel) Umbelliferae/Apiaceae (carrot family) Root Toxic to nymphal ticks (Ixodes scapularis (Say)) (LC50 = 0.744% wt : vol) USA [139]

Francoeuria crispa (Forsk.) Cass. (Francoeuria) Asteraceae (daisy/aster family) Aerial parts Diethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844 Egypt [138]

Gliricidia sepium Jacq. (Aaron's rod) Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae (hardy annual, legume bean/pea family)
Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Gnidia kraussiana Meissner Thymelaeaceae Root Acaricide Rwanda [151]

Gynandropsis gynandra (L.) Briq. (Chisaka-Luhya, Ejobyo-Luganda, and Akeyo-Luo) Capparidaceae Aerial parts/essential oil Repellent/toxic/killer Kenya [44, 104, 109, 118, 120]

Haplophyllum tuberculatum (Forsskål) A. H. L. Jussieu Rutaceae Aerial parts Essential oils showed toxicity effects to the larvae of Hyalomma dromedarii Koch, 1844 and Argas persicus Oken, 1818, adults Egypt [138]

Haematoxylum campechianum L. (logwood) Caesalpiniaceae/Leguminosae/Papilionaceae/
Fabaceae (hardy annual, legume bean/pea family)
Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition of Boophilus microplus Canst. Jamaica [58]

Hedeoma pulegioidesL. Pers. (American Pennyroyal, mock pennyroyal, squaw mint, tickweed, stinking balm, mosquito plant) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Leaf/flower Essential oil of American pennyroyal, tick repellent against Ixodes spp. USA [125, 169, 170]

Hibiscus rosa-sinensis L. (shoe black) Malvaceae (mallow family) Leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Hyacinthoides hispanica (P. Mill.) Rothm. (Endymion hispanicus (P. Mill.) Chouard) (bluebells, Spanish bluebells, Spanish squill) Liliaceae (lily family) Whole plant It is antitick plant and confidently help heal the problems brought about by ticks USA and South Africa Wanzala's personal communication with Annie Berthold-Bond in USA

Hydnora johannis Beccari Hydnoraceae Whole plant Acaricide Rwanda [151]

Hyparrhenia rufa (jaragua grass) Poaceae (grass family) Whole plant Weak toxic/repellent South America [128]

Hyptis verticillata Lamiaceae previously known as Labiatae (dead-nettle or mint family) Chemosterilant that inhibits oviposition and egg hatching Central America [171]

Impatiens stuhlmannii Warb. Balsaminaceae (balsam, impatiens family) Leaf Acaricide Rwanda [151]

Iphiona rotundifolia Asteraceae (also known as Compositae or daisy family) Leaf An acaricide infusion made from leaf Somali [61]

Jatropha curcas L. (Barbados nut, purging nut, and physic nut) Euphorbiaceae (spurge family) Leaf Infusion had a dipping and topical toxicity effect against Rhipicephalus appendiculatus ticks. Methanol extract repelled the ticks also South Africa [128]

Juglans nigra L. Juglandaceae Whole plant Repellent against Ixodes spp. USA [18, 167]

Juniperus occidentalis L (Western juniper) Cupressaceae (cypress family) Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.633 and 0.073% wt : vol, resp.) USA [139]

Juniperus virginiana L (Eastern red cedar) Cupressaceae (cypress family) Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.328 and 0.001% wt : vol, resp.) USA [139]

Justicia pectoralis L. (Fresh cut) Acanthaceae (carpenter grass) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of embryogenesis of Boophilus microplus Canst. Jamaica [58]

Kaliya, Pokot vernacular Fruit Fruit juice Kenya [153]

Lantana involucrata Roxb. (wild mint) Verbenaceae (vervain family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Laurencia obtusa (Hudson) J. V. Lamouroux, 1813 Rhodomelaceae Fresh leaf Topical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesis Jamaica [172]

Lavandula angustifolia (L. officinalis, L. spica, and L. vera) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Leaf/flower Lavender essential oil, tick repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]

Lepidium sativum Brassicaceae (cabbage family) Seed Crushed seeds mixed with cattle faeces and smeared on cattle Ethiopia [149]

Liagora elongate
Liagora farinosa J. V. Lamouroux 1816
Liagoraceae (rhodophytes) Whole plant Topical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesis Jamaica [172]

Lippia alba L. (colic Mint) Verbenaceae (vervain family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Lonchocarpus laxiflorus Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Floral parts Rotenoids act as acaricide USA [150]

Lupinus mutabilis Sweet (tarwi lupine/Adeans lupines/tarwi plant) Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Acaricide Europe [91]

Majorana hortensis Mönch (sweet marjoram) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Leaf A blend with lemon grass and tea tree essential oils forms antitick repellent spray New Zealand [160]

Mammea americana L. Clusiaceae/Guttiferae Fruit and leaf/seeds Toxic, sap/infusion in water/powdered seeds/decoction of seeds USA [18, 173]

Margaritaria discoidea (Baill.) G. L. Webster (pheasant-berry, egossa red pear, or bushveld peacock-berry) Phyllanthaceae (leaf-flower family) Latex Toxic/killer/acaricide. Oil hexane and water soluble extracts against the ticks Rhipicephalus appendiculatus and Amblyomma variegatum Kenya [174]

Melaleuca alternifolia Cheel. (tea tree oil) Myrtaceae (myrtle family) Leaf A blend with lemon grass and marjoram essential oils forms antitick repellent spray New Zealand [160]

Melia azedarach L. (Chinaberry, Persian lilac tree) Meliaceae (mahogany family) Fruit Extracts caused mortality of Boophilus microplus larvae and inhibited partially or totally egg production and embryogenesis in engorged females South America, Brazil [175]

Melicoccus bijugatus Jacq. Guinep. Synonym: Melicocca bijuga L. Sapindaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Melinis minutiflora Beauv. (molasses grass) Poaceae or Gramineae (the grass family) Whole plant (grass) Toxic/repellent. The plant repels ticks (Rhipicephalus appendiculatus and Boophilus microplus) South America, Caribbean, Kenya, Brazil, Mexico, Colombia, Central Africa, Southern Africa [107, 108, 119, 127, 130, 131, 134, 176], Cornell University Medicinal plants Homepage-2003

Melissa officinalis L. (lemon balm, balm, common balm, cytria, hashishat al nahil, kovanutu, ogulotu, seiyo-yama-hakka, sweet balm, toronjil, tronjan) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Aerial parts European pennyroyal essential oil, tick repellent against Ixodes spp. Europe and USA, Mecklenburg County, North Carolina [125]

Mesembryanthemus forsskale (Hochst) Aizoaceae Aerial parts Diethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844 Egypt [138]

Mentha × piperita L. (M. balsamea Willd.) (pepper mint) Piperaceae Oil repellents against Ixodes spp. USA [154]

Mentha pulegium L. (European pennyroyal, pulegium, run-by-the-ground, lurk-in-the-ditch, pudding grass, mosquito plant, fleabane, tickweed, squaw balm, squawmint tickweed) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Aerial parts European pennyroyal essential oil, tick repellent against Ixodes spp. Europe and USA, Mecklenburg County, North Carolina [125]

Mimosa pudica L. (shame mi lady or sensitive plant) Mimosaceae/Fabaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Momordica charantia L. (wild cerasee) Cucurbitaceae Leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Neorautanenia mitis (A. Rich) Verdc. Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Root Acaricide Rwanda [151]

Nerium oleander L. (Oleander) Apocynaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Nicotiana tabacum L., N. rustica, and N. glutinosa Solanaceae (nightshade family) Fresh leaf Leaf extract applied as acaricide. Toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. USA, Jamaica, and Kenya [18, 43, 58, 67, 150, 167]

Nicotiana tabacum L. (Tobacco) Solanaceae (nightshade family) Aerial part Aqueous extracts had immediate effect on mortality of engorged Rhipicephalus haemaphysaloides ticks and its fecundity production of females India [177]
Leaf Add Magadi soda to the leaf to make Kupetaba, antifeedant/growth disrupting/toxic/antiovipositant Kenya [43]
Whole plant A concoction mixed with sodom apple (Solanum incanum) to make an effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species) Kenya (Samburu pastoralists) in Baragoi [129]

Ocimum micranthum Wild. (wild parsley) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Ocimum suave Willd. Lamiaceae previously known as Labiatae (dead-nettle or mint family) Leaf Oil as repellent/acaricide Kenya, Tanzania [178180]

Olea europaea subsp. Cuspidata (African olive tree) Oleaceae (olive family) Whole plant A concoction mixed with Ilkerereai (Cadia purpurea) make effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species) Kenya (Samburu pastoralists) in Baragoi [129]

Oreopanax capitatus Jacq. (Aralia) Araliaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Padina vickerisiae Phaeophyceae (brown seaweeds) Whole plant Topical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesis Jamaica [172]

Peganum harmala L. Zygophyllaceae Aerial parts Extracts of petroleum ether, chloroform, ethyl acetate, and ethanol showed toxicity effects on engorged females of Boophilus annulatus Say, 1821 Egypt [138]

Pelargonium graveolens L'Hérit. or P. Odoratissimum (lemon plant/rose geranium/sweet scented geranium) Geraniaceae (the stork's bill family) Leaf/flower Rose geranium essential oil, tick repellent against Ixodes spp. Mecklenburg County, North Carolina, USA [125]

Pennisetum clandestinum (Kikuyu grass) Gramineae/Poaceae (grass family) Whole plant Weak toxic/repellent South America [108]

Pennisetum typhoides Gramineae/Poaceae (grass family) Corn and stem Powder/dust Southern Africa and Niger [127, 181]

Petiveria alliacea L. (Guinea hen) Phytolaccaceae Leaf, root Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Crude ethanol extracts exhibit some repellent activity against B. Microplus Canst. Dibenzyltrisulfide, a compound in the roots of P. alliacea, is acaricidal Jamaica; Central and South America, Caribbean and Africa [58, 182] Cornell University Medicinal plants Homepage-2003

Peucedanum angolense (Welw.) Apiaceae (carrot family) Leaf Acaricide Rwanda [151]

Physostigma mesoponticum Taub. Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Tuber, leaf, bark, root An infusion Malawi [96]

Phytolacca dodecandra L'Herit. Phytolaccaceae Leaf Juice; acaricide Rwanda, Ethiopia [149, 151]

Pimenta dioica L. (pimento) Myrtaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Pimenta racemosa (West Indian bay tree, bay rum tree, wild cinnamon, and bayberry) Myrtaceae Leaf Bay essential oil, repellent against ticks (Ixodes spp.) Mecklenburg County, North Carolina, USA [125]

Piper amalago L. (black jointer) Piperaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Piper auritum H. B. & K. Piperaceae Whole plant parts Juice USA [18]

Piper auritum H. B. & K. Piperaceae Whole plant Juice Central America [183]

Piper capense L. f. Piperaceae Leaf Acaricide Rwanda [151]

Piqueria trinervia Cav. Compositae Leaf/flower/root Piquerols A and B as acaricide against Boophilus microplus Canst. South America [184]

Pongamia pinnata Vent. (Indian beech, Pongam oil tree) Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Seed Pongamia essential oil is used as acaricide against Boophilus microplus Canst. India [145]

Pseudotsuga menziesii (Mirbel) Franco var. menziesii (formerly P. taxifolia) (Douglas-fir, Douglasfir) Pinaceae (pine family) Wood pitch Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol) USA [139]

Psiadia punctulata (DC) Vatke Asteraceae/Compositae (daisy family) Whole plant A concoction mixed with aloe (Aloe secundiflora) effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species) Kenya (Samburu pastoralists) in Baragoi [129]

Ptaeroxylon obliquum Radlk Ptaeroxylaceae An infusion of the powder as a wash Southern Africa [18, 127]

Ranunculus multifidus Forsk. Ranunculaceae (buttercup family) Fruit Acaricide Rwanda [151]

Reaumuria hirtella (Jaub. & Spach) Tamaricaceae Aerial parts Diethyl ether, ethyl acetate, hexane, and ethanol extracts showed toxicity against larvae of Hyalomma dromedarii Koch, 1844 Egypt [138]

Rhoicissus tridentata Vitaceae Plant parts Acaricide Rwanda [151]

Ricinus communis L. (castor oil plant) Euphorbiaceae (spurge family) Leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]
Seed Custard seed oil as an acaricide India [144]
Leaf Dichloromethane extracts were repellent to Rhipicephalus appendiculatus South Africa [128]

Rosmarinus officinalis L. (rosemary) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Leaf Rosemary essential oil, repellent against ticks (Ixodes spp.) Mecklenburg County, North Carolina, USA [125]

Stylosanthes scabra cv. Fitzroy or Seca Fabaceae (hardy annual, legume/pea family) Whole plant (grass) Toxic to Boophilus microplus Canst. South America [110]

Salvia serotina L./Wild. (little woman/chicken weed) Lamiaceae previously known as Labiatae (dead-nettle or mint family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Sambucus nigra spp. Canadensis (S. canadensis) L. (American Elder or elderberry/European elder) Adoxaceae/Caprifoliaceae (honeysuckle family) Leaf Extracts as acaricides USA [167]

Sambucus nigra spp. Canadensis (S. canadensis) L. (American Elder or elderberry/European elder) Adoxaceae/Caprifoliaceae (honeysuckle family) Leaf Leaf extract mixed with tobacco dust and Eucalyptus oil USA [18, 167]

Sclerocarya caffra Sond. Anacardiaceae Fruit Acaricide South Africa/East Africa/Madagascar [18, 127]

Securidaca longipedunculata Fres. Polygalaceae Plant Acaricide Rwanda [151]

Sequoia sempervirens L. (redwood, coast redwood, and California redwood) Taxodiaceae (bald cypress family)/Cupressaceae (cypress family) Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.1.673 and 0.079% wt : vol, resp.) USA [139]

Sequoiadendron giganteum (Lindl.) J. Buchholz (giant sequoia, big tree, giant redwood) Taxodiaceae Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol) USA [139]

Senna italica subsp. arachoides (Mill.) Goora wall. (Italian senna) Fabaceae (hardy annual, legume/pea family) Root The acaricidal activity of the ethyl acetate root extract increased significantly with concentration when tested against Hyalomma marginatum rufipes South Africa [185]

Sida acuta Burm. (broom weed) Malvaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Silybum marianum (L.) Gaertn. (Milk thistle) Asteraceae Aerial parts Extracts of petroleum ether, chloroform, ethyl acetate, and ethanol showed toxicity effects on engorged females of Boophilus annulatus Say, 1821 Egypt [138]

Simarouba glauca DC. (Bitter wood) Simaroubaceae (quassia family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Simmondsia chinensis (Link) C. K. Schneid. (jojoba, goat nut, deer nut, pignut, wild hazel, quinine nut, coffeeberry, or gray box bush) Simmondsiaceae Aerial parts Extracts caused motalities and affected reproductive physiology of the adult female tick, Boophilus annulatus Egypt [186]

Solanum dasyphyllum Schum. et Thonn. Solanaceae (nightshade family) Fruit, leaf, stem Acaricide Rwanda [151]

Solanum incanum (sodom apple) Solanaceae (nightshade family) Fruit Juice Ethiopia [149]
Whole plant A concoction mixed with tobacco (Nicotiana tabacum) to make an effective acaricide against brown ear tick (Rhipicephalus appendiculatus), red-legged tick (Rhipicephalus evertsii evertsi), Boophilus decoloratus, and bont tick (Amblyomma species) Kenya (Samburu pastoralists) in Baragoi [129]

Sorghum bicolor (L.) Moench (sorghum) Poaceae (grass family) Whole plant Extracts caused motalities and affected reproductive physiology of the adult female tick, Boophilus annulatus Egypt [186]
Aerial part Affects livestock ticks Kenya [47]

Spigelia anthelmia L. (worm grass) Loganiaceae (Logania family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Stachytarpheta jamaicensis Wild. (vervine) Verbenaceae (verbena/vervain family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Stemona collinsae Craib. Stemonaceae (Stemona family) Whole plant 50% concentration of extract caused 100 and 93.33% mortalities of engorged nymphs and adults of Boophilus microplus Canst., respectively Thailand [187]

Stemona tuberosa Lour. Stemonaceae (Stemona family) Whole plant 5% of chlorhydric acid extracts killed larvae of Rhipicephalus sanguineus, Boophilus microplus and Haemaphysalis intermedia ixodid ticks Vietnam [188]

Strychnos madagascariensis Poir. (black monkeys) Loganiaceae Leaf Infusion had a strong dipping and topical toxicity effect against Rhipicephalus appendiculatus ticks. The extract showed repellence activity against R. appendiculatus South Africa [128]

Stylosanthes hamata cv. Verano. Fabaceae (pea family) Whole plant (grass) Toxic/repellent against Boophilus microplus Canst. South America, [189192]
Australia [110, 111]

Stylosanthes humilis H. B. K. Fabaceae (pea family) Whole plant (grass) Toxic/repellent against Boophilus microplus Canst. South America [189192]

Stylosanthes scabra Vogel. (shrubby stylo) Fabaceae (pea family) Whole plant Extracts caused a high larval mortality of Rhipicephalus sanguineus, Boophilus microplus, and Haemaphysalis intermedia ixodid ticks India [193]

Stypopodium lobalum (C. Agardh) Kützing. Dictyotaceae (thalloid brown alga) Whole plant Topical application of crude ethanol extract affected the survival of engorged and adult female Boophilus microplus Canst. and inhibited its oviposition and embryogenesis Jamaica [172]

Symphytum officinale L. (Comfrey) Boraginaceae (borage family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica, USA [58]

Tabernaemontana johnstonii Apocynaceae Acaricide Rwanda [151]

Tagetes minuta L. (marigold) Asteraceae (daisy family). Aerial parts Extracted essential oil had significant repellent effect against Rhipicephalus appendiculatus adult ticks Kenya [47, 194]
Extracted essential oil had significant repellent effect against Hyalomma rufipes adult ticks South Africa [195]

Tagetes patula French (marigold, dwarf marigold, or dwarf French marigold) Asteraceae (daisy family) Rwanda [151]

Tamarindus indicus L. (tamarind) Caesalpiniacae (gulmohar family) Mature fruit Water and 10% ethanol crude extracts caused mortality of engorged female, Boophilus microplus Canst.
Organic acids in tamarind fruits (oxalic, malic, succinic, citric and tartaric acids) also caused mortality of B. microplus Canst.
Thailand [196]

Tanacetum vulgare Asteraceae ([also known as Compositae] daisy family) Whole plant Essential oils are acaricidal Europe, Eastern North America http://www.florahealth.com/home_int.cfm

Taxodium distichum (L.) L. C. Rich. (bald cypress and swamp Cypress) Taxodiaceae (bald cypress family) Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) at >2% concentration (wt : vol) USA [139]

Tephrosia leiocarpa A. Gray Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Root Acaricide North America [197]

Tephrosia vogelii Hook F. Fabaceae/Papilionaceae/Leguminosae (hardy annual, legume/pea family) Leaf, root, pod, seed, bark, whole plant Rotenoids present in an infusion acts like modern dips. Toxic to 1-, 2-, and 3-host ticks Cameroon, USA, Malawi, Tanzania [18, 150, 198202]

Thuja plicata Donn ex D. Don in Lambert 1824 (Western/giant red cedar, giant arborvitae, shinglewood, canoe cedar) Cupressaceae (cypress family) Heartwood and leaves Toxic to nymphal and larval ticks (Ixodes scapularis (Say)) (LC50 = 0.821 and 0.022% wt : vol, resp.) USA [139]

Thylachium africanum Lour. Capparidaceae Aerial parts/oil Repellency of their essential oil Kenya [104]

Turnera ulmifolia L. (ramgoat dashalong) Turneraceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Turpentine, name applied to numerous semifluid, yellow or brownish oleoresins obtained from various coniferous trees in Asia, Europe, and America Turpentine, Syncarpia glomulifera Myrtaceae Acaricide USA [150]

Urena lobata L. (bur mallow) Malvaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Vernonia amygdalina L. (bitter-leaf tree) Asteraceae (also known as Compositae or daisy family) Leaf Juice Ethiopia [149]

Vitex agnus-castus L. (chaste tree, chasteberry, Abraham's balm, or monk's pepper) Lamiaceae Aerial parts Ethanol, propylene carbonate, Vitex agnus-castus concentrate, topical application, repelling horseflies, flies and mosquitoes Switzerland [203]

Wedelia trilobata L. (yellow marigold) Asteraceae (also known as Compositae or daisy family) Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]

Zingiber officinale Wild. (Ginger) Zingiberaceae Fresh leaf Topical application of crude ethanol extracts. Being toxic and inhabitant of oviposition and embryogenesis of Boophilus microplus Canst. Jamaica [58]