Table 3.
Cancer-specific survival by stage, size, grade, and necrosis (SSIGN) score for patients in the contemporary radical nephrectomy cohort: observed and competing risk adjusted rates
| Score | n† | Cancer-specific survival rates* | |||||
|---|---|---|---|---|---|---|---|
| Year 1 | Year 3 | Year 5 | Year 7 | Year 10 | Year 15 | ||
| 0–1 | 161 | 100; 100 (157) | 100; 100 (147) | 99; 99 (127) | 99; 99 (104) | 97; 98 (65) | 97; 98 (10) |
| 2 | 86 | 100; 100 (81) | 99; 99 (72) | 97; 98 (65) | 97; 98 (57) | 97; 98 (33) | 90; 92 (4) |
| 3 | 129 | 100; 100 (125) | 99; 99 (114) | 98; 98 (101) | 97; 98 (76) | 89; 91 (42) | 89; 91 (10) |
| 4 | 80 | 99; 99 (78) | 92; 92 (66) | 88; 88 (53) | 84; 86 (44) | 80; 82 (26) | 71; 77 (3) |
| 5 | 102 | 97; 97 (97) | 86; 86 (80) | 74; 75 (61) | 68; 70 (38) | 59; 63 (20) | 49; 56 (3) |
| 6 | 39 | 92; 92 (34) | 76; 76 (28) | 70; 71 (23) | 70; 71 (18) | 50; 53 (8) | 40; 45 (1) |
| 7 | 127 | 87; 87 (108) | 62; 63 (72) | 51; 54 (52) | 46; 49 (31) | 45; 48 (20) | 21; 35 (1) |
| 8 | 14 | 79; 79 (10) | 35; 43 (4) | 27; 36 (3) | 18; 29 (2) | NA | NA |
| 9 | 108 | 78; 78 (81) | 46; 48 (45) | 35; 38 (29) | 29; 32 (18) | 20; 26 (5) | NA |
| ≥10 | 156 | 59; 59 (90) | 31; 32 (46) | 15; 16 (21) | 9; 11 (10) | 6; 8 (7) | NA |
NA = not applicable because no patients were left at risk; RCC = renal cell carcinoma.
*
Two rates are presented. The first is the cancer-specific survival rate estimated using the Kaplan-Meier method; the second is the rate after accounting for the competing risk of death from non-RCC causes. Number of patients at risk is denoted in parentheses.
†
Total = 1002; 36 patients excluded for unknown cause of death.