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Polymer and polyplex preparation.
Notes: (A) Synthesis of FA-PEG-SS-PEI polymer; (B) formation of FA-PEG-SS-PEI-SPION/siRNA polyplex.
Abbreviations: FA, folic acid; PEG, polyethylene glycol; SS, disulfide; PEI, polyethylenimine; SPION, superparamagnetic iron oxide nanoparticle; DMAP, dimethylaminopyridine; NHS, N-hydroxysuccinimide; DCC, dicyclohexylcarbodiimide.
