Figure 7.
In vitro MRI of SGC-7901 cells.
Notes: (A) T2-weighted and color T2-mapping images and (B) T2 relaxation time of SGC-7901 cells treated with PEG-SS-PEI-SPION/siScr and FA-PEG-SS-PEI-SPION/siScr at Fe concentrations of 0, 5, 10, 20, 40, and 80 μg/mL. *P<0.05, **P<0.01 versus PP/siScr (n=3).
Abbreviations: MRI, magnetic resonance imaging; FA, folic acid; PEG, polyethylene glycol; SS, disulfide; PEI, polyethylenimine; SPION, superparamagnetic iron oxide nanoparticle; siScr, scrambled siRNA; PP, PEG-SS-PEI-SPIONs; FP, FA-PEG-SS-PEI-SPIONs.