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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Stroke. 2017 May 11;48(6):1444–1450. doi: 10.1161/STROKEAHA.116.015677

Table 2. Replicated SNPs across other GWAS studies.

Ch. SNP BP1 P-value VISP Gene Replication2 Found in Vascular Trait2,3 Found in Other Trait(s)2,4
vWF
9 rs2519093 136142120 1.53E-21 ABO - + 1
9 rs495828 136155117 2.88E-17 ABO - + 1
9 rs4962153 136324004 5.54E-08 ABO - - 1
9 rs657152 136139515 7.22E-26 ABO - 1
9 rs505922 136149479 2.32E-30 ABO + + 4
9 rs507666 136149649 2.36E-21 ABO - - 1
9 rs579459 136154418 2.46E-17 ABO - + 7
9 rs612169 136143692 7.92E-29 ABO - - 1
9 rs644234 136142467 1.35E-25 ABO - - 1
9 rs649129 136154554 2.76E-17 ABO - - 1
9 rs651007 136154125 2.60E-17 ABO - - 3
9 rs657152 136139515 7.22E-26 ABO - + 5
9 rs687289 136137356 3.93E-30 ABO + - -
9 rs687621 136137315 6.83E-30 ABO - + 1
9 rs8176743 136131665 1.84E-10 ABO + - -
9 rs8176749 136131438 9.24E-11 ABO + - 2
9 rs8176746 136131322 4.00E-8 ABO + - 1
1

Human genome Feb. 2009 (GRCh37/hg19) Assembly.

2

NHGRI catalog of published genome-wide association studies(http://www.genome.gov/gwastudies/ [access date 09/01/16) replication of vWF levels.

3

Significant in GWAS of vascular trait (i.e. cardiovascular disease, venous thrombosis).

4

Significant in GWAS of other clinical phenotypes. Expanded in Supplemental Table III.