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. 2017 Jul 31;12(7):e0182142. doi: 10.1371/journal.pone.0182142

Fig 2. Enhanced nicotine oral SA in mice with vMB α4 deletion.

Fig 2

a) Mean (± SEM) nicotine intake (mg/kg) over 4 days is shown for each nicotine concentration, in male and female α4-flox GFP(+) (n = 26) and Cre(+) (n = 24) mice. *p<0.05. b) Mean (± SEM) nicotine intake ratio (fraction of nicotine-containing fluid consumed relative to total fluid consumed) over 4 days is shown for each nicotine concentration in α4-flox GFP(+) and Cre(+) mice. c) Mean (± SEM) intake of nicotine solution (mL/kg), used to calculate mass of nicotine intake shown in (a), is shown for each nicotine concentration in α4-flox GFP(+) and Cre(+) mice. d) Mean (± SEM) water intake (mL/kg) over 4 days is shown for each nicotine concentration in α4-flox GFP(+) and Cre(+) mice. e) Mean (± SEM) total fluid intake (mL/kg) over 4 days is shown for each nicotine concentration in GFP(+) and Cre(+) mice. f) Mean (± SEM) body weight (g) for α4-flox GFP(+) and Cre(+) mice is shown for each nicotine concentration. S2, S3 and S4 Figs show intake data separated by sex.