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Heterologous head-to-tail pairing between boundaries in cis. A: Schematic of the eve regulatory region. Boundaries: nhomie (orange), homie (brown), others are not specified. B: Interaction between nhomie-homie and other flanking boundaries generates independent stem-loops that are separated by unanchored segments. C: The nhomie-homie pair interacts with their neighbors. D: The interactions between boundaries are further stabilized by homolog pairing.
