Table 3.
Cognitive Test Z-Scores (Means and Standard Deviations)
Measures | All Patients (N=28) | fTBI+Chemo (N=9) | Chemo Alone (N=19) | Controls (N=10) | ||||
---|---|---|---|---|---|---|---|---|
PRE | POST | PRE | POST | PRE | POST | PRE | POST | |
Attention/Executive | ||||||||
DF | 0.3 (0.9) | 0.4 (1.0) | 0.4 (0.9) | 0.4 (1.0) | 0.3 (0.9) | 0.3 (1.0) | 0.8 (0.8) | 1.1 (0.6) |
DB | 0.4 (0.9) | 0.3 (1.0) | 0.3 (0.8) | 0.0 (1.0) | 0.5 (0.9) | 0.5 (0.9) | 0.7 (1.0) | 1.0 (1.2) |
BTA | −0.1 (0.9) | −0.4 (1.1) | 0.0 (0.8) | −0.3 (1.3) | −0.1 (0.9) | −0.4 (1.0) | 0.1 (1.0) | 0.4 (0.6) |
TMTA | −0.1 (0.6) | −0.1 (0.9) | −0.2 (0.7) | 0.0 (0.9) | −0.1 (0.6) | −0.2 (0.9) | 0.3 (1.2) | 1.1 (1.3)* |
TMTB | −0.05 (0.9) | 0.02 (0.8) | −0.2 (0.8) | −0.2 (0.6) | 0.0 (1.0) | 0.2 (0.8) | 0.4 (1.4) | 1.0 (1.6) |
Verbal Memory | ||||||||
CVLT-L | 0.5 (0.6) | 1.2 (0.7)* | 0.4 (0.6) | 1.2 (1.1)* | 0.5 (0.5) | 1.2 (0.8)* | 1.4 (0.6) | 2.0 (0.9)* |
CVLT-LD | 0.5 (0.7) | 0.8 (1.0) | 0.4 (0.7) | 0.6 (1.1) | 0.6 (0.7) | 0.9 (1.0)* | 0.8 (0.5) | 1.3 (0.5)* |
CVLT-DI | 0.6 (0.8) | 0.7 (0.9) | 0.7 (0.4) | 0.4 (0.8) | 0.5 (0.9) | 0.8 (0.9)* | 0.8 (0.5) | 0.7 (0.8) |
Visual Memory | ||||||||
BLT-L | −0.2 (1.2) | 0.2 (1.1)* | 0.2 (1.5) | 0.3 (1.3) | −0.4 (1.1) | 0.2 (1.0)* | −0.3 (1.4) | 0.8 (1.6)* |
BLT-LD | −0.3 (1.3) | −0.1 (1.3) | 0.5 (1.1) | 0.2 (1.6) | −0.6 (1.2) | −0.3 (1.1) | −0.1 (1.2) | 0.5 (1.0)* |
BLT-DI | 0.2 (1.3) | −0.1 (1.4) | 0.4 (1.2) | −0.1 (1.4)* | 0.1 (1.3) | −0.1 (1.5) | −0.4 (0.3) | 0.4 (1.1)* |
DF= Digit Span Forward; DB= Digit Span Backward; BTA= Brief Test of Attention; TMTA= Trail Making Test A; TMTB= Trail Making Test B; CVLT-L= California Verbal Learning Test- Learning; CVLT-LD= California Verbal Learning Test- Long Delay; CVLT-DI= California Verbal Learning Test- Discrimination Index; BLT-L= Brown Location Test- Learning; BLT-LD= Brown Location Test-Long Delay; BLT-DI=Brown Location Test-Discrimination Index.
Indicates significant within-group difference (p < 0.05) between the pre- and post-HSCT scores on the given cognitive test.