Skip to main content
. 2017 Jul 17;13(7):e1006899. doi: 10.1371/journal.pgen.1006899

Fig 2. Conditional deletion of the Rrn3 gene inhibits RPI transcription but does not affect pre-initiation complex formation.

Fig 2

As in Fig 1., A) and B) show the ChIP enrichment profile maps before (Rrn3+) and after (Rrn3-) Rrn3 gene inactivation (72h 4-HT time point, S3B and S3F Fig). The binding profiles (IP) for Rrn3, RPI, UBF, the SL1 components TAF1B and TBP, and TTF1 are shown in A) over the functional mouse rRNA gene unit and, B) at higher resolution for the upstream Enhancer and Promoter elements and the 47S termination site, (boxed regions in A). As in Fig 1, a scale map of the rDNA sequence elements is given below each panel, and ChIP enrichments for each factor are given as; ChIP-Seq RPM/Input DNA RPM.