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. 2017 Jul 17;13(7):e1006899. doi: 10.1371/journal.pgen.1006899

Fig 3. Conditional deletion of the UBF gene not only ablates RPI transcription but also prevents preinitiation complex formation.

Fig 3

A) and B) show the ChIP enrichment profile maps before (UBF+) and after (UBF-) UBF gene inactivation (72h 4-HT time point, S3E and S3F Fig). The binding profiles (IP) for UBF RPI, Rrn3, the SL1 component TAF1C, and TTF1 are shown; A) over the functional mouse rRNA gene unit and, B) at higher resolution for the upstream Enhancer and Promoter elements and the 47S termination site. As in Fig 1, a scale map of the rDNA sequence elements is given below each panel, and ChIP enrichments for each factor are given as; ChIP-Seq RPM/Input DNA RPM.