Table 3. Dissolution parameters of pure FFA and its SDs prepared using different carriers at drug-carrier ratio of 1: 5.
System | IRD (%) | DE60 (%) | RDR60 (%) |
---|---|---|---|
Pure MA | 39.46 | 42.48 | - |
MA-GLU (1: 5) | 25.20 | 34.95 | 0.95 |
MA-PF (1: 5) | 19.30 | 44.98 | 1.21 |
MA-PEG 4000 (1: 5) | 60.15 | 59.40 | 1.26 |
MA-EPO (1: 5) | 23.19 | 22.48 | 0.51 |
IRD (%): Initial dissolution rate (after 15 min)
DE60 (%): Dissolution efficiency after 60 min
RDR60(%): Relative dissolution rate after 60 min