Table 1. Characteristics of fibroid cases and controls in the Vanderbilt University Synthetic Derivative (SD) and CARDIA.

Participants	Synthetic Derivativea		P	CARDIAb		P
	All cases	All controls		All cases	All controls
Continuous	Mean (SD)	Mean (SD)		Mean (SD)	Mean (SD)
Age	45.9 (11.5)	39.5 (16.1)	<0.0001	42.3 (3.6)	41.9 (3.8)	0.028
BMI	32.4 (9.7)	30.4 (8.7)	<0.0001	30.9 (7.6)	28.9 (8.2)	0.0001
Categorical	N (%)	N (%)		N (%)	N (%)
Race			<0.001			<0.001
Black	1,309 (32.7)	2,573 (20.8)		398 (65.6)	147 (33.0)
White	2,698 (67.3)	9,783 (79.2)		209 (34.4)	299 (67.0)
BMI			<0.001			<0.001
<25kg/m2	846 (21.1)	3,728 (31.2)		144 (23.7)	182 (40.8)
25–30 kg/m2	1,048 (26.2)	3,318 (26.8)		179 (29.5)	99 (22.2)
30–35 kg/m2	867 (21.6)	2,360 (19.1)		128 (21.1)	80 (17.9)
>35 kg/m2	1,246 (31.1)	2,950 (23.9)		156 (25.7)	85 (19.1)
Participants	BioVUc			CARDIAd
	AA GWAS Cases	AA GWAS Controls		AA GWAS Cases	AA GWAS Controls
Continuous	Mean (SD)	Mean (SD)		Mean (SD)	Mean (SD)
Age	40.6 (10.9)	41.7 (15.5)	0.144	40.0 (3.7)	39.0 (4.2)	0.763
BMI	33.4 (8.8)	31.8 (8.5)	0.001	32.9 (7.9)	31.4 (8.3)	0.380
Average European Ancestry (%)	17.5 (10.1)	19.2 (12.5)	0.008	14.8 (9.7)	17.5% (11.5)	0.112
Categorical	N (%)	N (%)	0.009	N (%)	N (%)
BMI						0.054
<25kg/m2	83 (15.4)	141 (20.3)		33 (12.5)	36 (24.7)
25–30 kg/m2	137 (25.4)	201 (29.0)		76 (28.8)	41 (28.1)
>30 kg/m2	319 (59.2)	352 (50.7)		155 (58.7)	69 (47.3)

^a Includes all eligible participants at Vanderbilt Synthetic Derivative (SD) with or without GWAS data;

^b Eligible CARDIA participants with or without GWAS data;

^c Subset of African Americans in the SD with available GWAS data;

^d Subset of African Americans in CARDIA with available GWAS data; AA = African Americans