Table 2.
Demographic and clinical characteristics of Chinese patients who underwent coronary angiography and were diagnosed with coronary heart disease, subdivided into patients with stable angina pectoris, unstable angina pectoris, or acute myocardial infarction
| Patient subgroup |
||||
|---|---|---|---|---|
| Parameter | Stable angina pectoris (n = 65) | Unstable angina pectoris (n = 254) | Acute myocardial infarction (n = 72) | Statistical significance |
| Age, years | 64 (42–82) | 62 (33–83) | 59 (30–83) | NS |
| Sex, male | 40 (61.5) | 171 (67.3) | 53 (73.6) | NS |
| Diabetes | 21 (32.3) | 77 (30.3) | 23 (31.9) | NS |
| Hypertension | 36 (55.4) | 180 (70.9) | 44 (61.1) | P = 0.035b |
| Smoking | 32 (49.2) | 138 (54.3) | 47 (65.3) | NS |
| BMI, kg/m2 | 27.2 (20.6–33.2) | 25.8 (18.4–33.5) | 26.0 (19.0–48.6) | NS |
| Total cholesterol, mmol/l | 4.27 (1.94–7.33) | 4.69 (1.92–8.07) | 4.43 (0.86–7.04) | P = 0.030b |
| Triglycerides, mmol/l | 1.36 (0.52–0.41) | 1.565 (0.48–11.69) | 1.55 (0.74–9.68) | NS |
| HDL-C, mmol/l | 1.13 (0.52–2.09) | 1.31 (0.33–3.33) | 1.13 (0.66–2.34) | P < 0.001b |
| LDL-C, mmol/l | 2.38 (0.75–4.07) | 2.55 (0.60–5.34) | 2.66 (0.24–4.53) | NS |
| Lipoprotein(a), g/l | 0.20 (0.05–0.74) | 0.2 (0.03–0.92) | 0.23 (0.02–0.79) | NS |
| Fibrinogen, g/l | 3.39 (2.44–4.97) | 3.46 (1.63–8.72) | 3.48 (2.18–7.51) | NS |
| CRP, ng/l | 0.4 (0.1–9.5) | 0.66 (0–26.5) | 1.6 (0.1–52.07) | P < 0.001c |
| Lp-PLA2, µg/l | 266.44 (46.43–476.83) | 250.58 (8.75–762.94) | 249.46 (8.75–502.28) | NS |
| ≥ 292 µg/la | 23 (35.4) | 82 (32.3) | 18 (25.0) | NS |
| Probucol treatment | 2 (3.1) | 30 (11.8) | 17 (23.6) | P = 0.001d |
Data presented as median (range) or n (%) prevalence.
BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CRP, C-reactive protein; Lp-PLA2, lipoprotein-associated phospholipase A2.
292 µg/l represents the upper quartile of Lp-PLA2 concentration in all patients.
Patients with unstable angina pectoris versus other groups; cpatients with acute myocardial infarction versus other groups;dpatients with unstable angina pectoris or acute myocardial infarction versus stable angina pectoris.
NS, no statistically significant between-group difference (P > 0.05; Student’s independent t-test, one-way analysis of variance or χ2-test, as appropriate).