Table 4.
Multivariate logistic regression analysis of risk factors for coronary heart disease (CHD) in 531 Chinese patients who underwent diagnostic coronary angiography for evaluation of CHD
| Adjusted |
Unadjusted |
|||||
|---|---|---|---|---|---|---|
| Characteristic | OR | 95% CI | Statistical significance | OR | 95% CI | Statistical significance |
| Age, years | 1.056 | 1.025, 1.088 | P < 0.001 | |||
| Sex, female | 0.201 | 0.111, 0.362 | P < 0.001 | |||
| Diabetes | 3.592 | 1.887, 6.837 | P < 0.001 | 2.889 | 1.608, 5.191 | P < 0.001 |
| Hypertension | 1.029 | 0.598, 1.769 | NS | 1.407 | 0.861, 2.299 | NS |
| Smoking | 1.473 | 0.834, 2.601 | NS | 2.271 | 1.407, 3.667 | P = 0.001 |
| Triglycerides, mmol/l | 1.111 | 0.897, 1.376 | NS | 1.031 | 0.863, 1.233 | NS |
| HDL-C, mmol/l | 0.561 | 0.273, 1.154 | NS | 0.584 | 0.304, 1.124 | NS |
| Fibrinogen, g/l | 1.396 | 0.994, 1.962 | NS | 1.353 | 0.997, 1.836 | NS |
| CRP, ng/l | 1.224 | 1.046, 1.433 | P = 0.012 | 1.248 | 1.068, 1.458 | P = 0.005 |
| Lp-PLA2 ≥ 292 µg/la | 2.814 | 1.519, 5.214 | P = 0.001 | 2.391 | 1.349, 4.239 | P = 0.003 |
OR, odds ratio; CI, confidence interval; HDL-C, high-density lipoprotein cholesterol; CRP, C-reactive protein; Lp-PLA2, lipoprotein-associated phospholipase A2.
a
292 µg/l represents the upper quartile of Lp-PLA2 concentration in all patients.
NS, no statistically significant association (P > 0.05).