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CPT decreases the expression of proteins encoded by STAT3-regulated genes in SGC7901 cells. (A) SGC7901 cells were treated with indicated concentrations of CPT for 24 h and then subjected to western blotting to detect Bcl-xL, Mcl-1, survivin, and XIAP. (B) SGC7901 cells were treated with 15 µM CPT, 0.5 µg/mL DOXO, or CPT combined with DOXO for 24 h. Cell lysates were subjected to western blotting using antibodies against Bcl-xL, Mcl-1, survivin, XIAP, and ACTB (internal control).
