Table 1.
Association between the presence of colorectal adenomas (CRA) or advanced colorectal adenomas (A-CRA) and serum folate levels in the overall study population (n = 1310) that was screened at the start of the study for the presence of CRA.
| Group | n | Age, years | Statistical significancea | Serum folate, ng/ml | Statistical significancea | |
|---|---|---|---|---|---|---|
| Total | Without CRA | 888 | 56.78 ± 12.02 | 7.76 ± 4.25 | ||
| CRA | 422 | 58.78 ± 12.08 | P = 0.005 | 7.26 ± 3.67 | P = 0.029 | |
| A-CRA | 135 | 58.74 ± 12.62 | P = 0.020 | 6.95 ± 3.72 | P = 0.002 | |
| Males | Without CRA | 381 | 54.63 ± 13.55 | 7.11 ± 3.99 | ||
| CRA | 225 | 56.01 ± 12.86 | NS | 6.78 ± 3.95 | NS | |
| A-CRA | 83 | 58.23 ± 13.35 | NS | 6.43 ± 3.15 | NS | |
| Females | Without CRA | 507 | 57.37 ± 10.70 | 8.24 ± 4.57 | ||
| CRA | 197 | 60.01 ± 11.02 | 0.004 | 7.80 ± 3.70 | NS | |
| A-CRA | 52 | 59.56 ± 11.45 | NS | 7.78 ± 4.40 | NS | |
Data presented as mean ± SD.
a
Compared with healthy participants without CRA at baseline (Without CRA group); Student’s t-test.
CRA, colorectal adenoma; A-CRA, advanced colorectal adenoma; NS, no significant difference (P > 0.05).