Table 2.
Potential predictive factors for rectal pain.
| All patients (n = 288) | Group N (n = 249) | Group P (n = 39) | Univariate |
Multivariate |
||||
|---|---|---|---|---|---|---|---|---|
| 95% CI | P value | 95% CI | P value | OR | ||||
| Age, years | 60.7 ± 11.1 | 61.0 ± 11.1 | 58.3 ± 11.0 | 0.949–1.008 | 0.148 | |||
| < 60 | 125 (43.4) | 104 (41.8) | 21 (53.9) | |||||
| ≥60 | 163 (56.6) | 145 (58.2) | 18 (46.2) | |||||
| Sex, M/F | 177/111 | 153/96 | 24/15 | 0.502–2.009 | 0.991 | |||
| Height, cm | 162.1 ± 8.6 | 161.9 ± 8.5 | 163.5 ± 9.6 | 0.982–1.065 | 0.478 | |||
| Weight, kg | 60.7 ± 10.5 | 60.5 ± 10.5 | 61.7 ± 10.5 | 0.979–1.044 | 0.497 | |||
| BMI, kg/m2 | 23.0 ± 3.0 | 23.0 ± 3.0 | 23.0 ± 3.2 | 0.903–1.128 | 0.877 | |||
| <25 | 218 (75.7) | 187 (75.1) | 31 (79.5) | 0.553 | ||||
| ≥25 | 70 (24.3) | 62 (24.9) | 8 (20.5) | |||||
| Charlson comorbidity index | 2.9 ± 1.5 | 2.9 ± 1.5 | 3.0 ± 1.6 | 0.863–1.324 | 0.545 | |||
| Presence of diabetes mellitus | 46 (16.0) | 44 (17.7) | 2 (5.1) | 0.064 | 1.107–28.980 | 0.037 | 5.663 | |
| Preoperative CRT | 63 (21.9) | 46 (18.5) | 17 (43.6)* | 1.678–6.931 | <0.001 | 0.431–3.111 | 0.771 | 1.158 |
| Pathological stage | ||||||||
| I | 104 (36.1) | 88 (35.3) | 16 (41.0) | 0.123–9.781 | 0.450 | |||
| II | 54 (18.8) | 48 (19.4) | 6 (15.4) | 0.077–7.338 | ||||
| III | 104 (36.1) | 93 (37.5) | 11 (28.2) | 0.078–6.452 | ||||
| IV | 25 (8.7) | 19 (7.7) | 6 (15.4) | 0.189–19.039 | ||||
| Preoperative pain (NRS) | 0.6 ± 1.8 | 0.2 ± 1.1 | 0.3 ± 1.2 | 0.830 | ||||
| Operation time, min | 177.0 ± 61.3 | 168.6 ± 55.1 | 230.4 ± 72.1* | 1.008–1.018 | <0.001 | 1.006–1.018 | <0.001 | 1.012 |
| Ileostomy | 61 (24.5) | 45 (18.6) | 16 (41.0)* | 1.489–6.229 | 0.001 | |||
| Maximum tumor size of >4 cm | 92 (36.9) | 81 (32.7) | 11 (28.2) | 0.384–1.708 | 0.580 | |||
| Anastomotic margin of ≤2 cm from anal verge | 39 (15.7) | 23 (9.2) | 16 (41.0)* | 3.155–14.683 | <0.001 | 2.475–13.542 | <0.001 | 5.790 |
| Length of hospital stay, days | 7.7 ± 5.4 | 7.4 ± 4.3 | 10.1 ± 9.7* | 1.013–1.117 | 0.013 | 0.966–1.109 | 0.324 | 1.035 |
| Anastomotic leakage | 13 (4.5) | 8 (3.2) | 5 (12.8)* | 1.370–14.326 | 0.013 | 0.454–12.280 | 0.306 | 2.362 |
All data are presented as mean ± SD or n (%) patients. M/F: male/female; BMI: body mass index; CRT: chemoradiotherapy; NRS: numeric rating scale; CI: confidence interval; OR: odds ratio, Group N: patients without postoperative rectal pain; Group P: patients with postoperative rectal pain. *P < 0.05 compared with Group N.