Table 3.
Number | microRNA | Expression | Statistical significancea | Fold change |
---|---|---|---|---|
Fold change >2 (or <0.5) fold with P < 0.05 | ||||
1 | hsa-miR-27a-3p | Down | P = 0.009 | 0.03 |
2 | hsa-miR-205-5p | Down | P = 0.019 | 0.10 |
3 | hsa-miR-200a-3p | Down | P = 0.004 | 0.13 |
4 | hsa-miR-122-5p | Down | P = 0.034 | 0.13 |
5 | hsa-miR-885-5p | Down | P = 0.024 | 0.13 |
6 | hsa-miR-375 | Down | P = 0.001 | 0.14 |
7 | hsa-miR-10a-5p | Down | P = 0.007 | 0.16 |
8 | hsa-miR-151a-3p | Down | P = 0.023 | 0.16 |
9 | hsa-let-7f-5p | Down | P = 0.001 | 0.17 |
10 | hsa-miR-195-5p | Down | P < 0.001 | 0.17 |
11 | hsa-miR-146b-5p | Down | P = 0.042 | 0.18 |
12 | hsa-let-7c | Down | P < 0.001 | 0.19 |
13 | hsa-miR-92b-3p | Down | P = 0.012 | 0.21 |
14 | hsa-miR-142-3p | Down | P < 0.001 | 0.21 |
15 | hsa-miR-99a-5p | Down | P = 0.005 | 0.21 |
16 | hsa-let-7e-5p | Down | P = 0.001 | 0.21 |
17 | hsa-miR-331-3p | Down | P = 0.019 | 0.21 |
18 | hsa-miR-605 | Down | P = 0.016 | 0.22 |
19 | hsa-miR-125b-5p | Down | P = 0.027 | 0.22 |
20 | hsa-miR-335-5p | Down | P = 0.012 | 0.22 |
21 | hsa-miR-194-5p | Down | P = 0.013 | 0.23 |
22 | hsa-miR-424-5p | Down | P = 0.003 | 0.23 |
23 | hsa-miR-382-5p | Down | P = 0.016 | 0.24 |
24 | hsa-miR-376a-3p | Down | P = 0.040 | 0.25 |
25 | hsa-miR-30d-5p | Down | P = 0.003 | 0.25 |
26 | hsa-miR-152 | Down | P = 0.011 | 0.26 |
27 | hsa-miR-99b-5p | Down | P = 0.006 | 0.27 |
28 | hsa-miR-30a-5p | Down | P = 0.002 | 0.27 |
29 | hsa-miR-15a-5p | Down | P = 0.004 | 0.28 |
30 | hsa-miR-28-5p | Down | P = 0.004 | 0.28 |
31 | hsa-miR-23b-3p | Down | P = 0.004 | 0.28 |
32 | hsa-miR-584-5p | Down | P = 0.004 | 0.29 |
33 | hsa-miR-339-5p | Down | P = 0.027 | 0.30 |
34 | hsa-miR-27b-3p | Down | P = 0.003 | 0.30 |
35 | hsa-miR-145-5p | Down | P = 0.020 | 0.31 |
36 | hsa-let-7a-5p | Down | P < 0.001 | 0.31 |
37 | hsa-miR-30e-3p | Down | P = 0.012 | 0.32 |
38 | hsa-miR-766-3p | Down | P = 0.017 | 0.32 |
39 | hsa-miR-30c-5p | Down | P < 0.001 | 0.32 |
40 | hsa-miR-30e-5p | Down | P = 0.003 | 0.32 |
41 | hsa-miR-139-5p | Down | P = 0.029 | 0.33 |
42 | hsa-miR-126-3p | Down | P = 0.002 | 0.33 |
43 | hsa-miR-107 | Down | P = 0.025 | 0.33 |
44 | hsa-miR-26a-5p | Down | P = 0.004 | 0.34 |
45 | hsa-miR-151a-5p | Down | P = 0.001 | 0.35 |
46 | hsa-miR-146a-5p | Down | P = 0.003 | 0.35 |
47 | hsa-miR-125a-5p | Down | P = 0.049 | 0.35 |
48 | hsa-miR-103a-3p | Down | P = 0.004 | 0.36 |
49 | hsa-let-7d-5p | Down | P < 0.001 | 0.36 |
50 | hsa-miR-374b-5p | Down | P = 0.001 | 0.38 |
51 | hsa-miR-374a-5p | Down | P = 0.014 | 0.39 |
52 | hsa-miR-320a | Down | P = 0.046 | 0.39 |
53 | hsa-miR-21-5p | Down | P = 0.016 | 0.40 |
54 | hsa-miR-15b-5p | Down | P = 0.023 | 0.41 |
55 | hsa-miR-155-5p | Down | P = 0.003 | 0.41 |
56 | hsa-miR-28-3p | Down | P = 0.003 | 0.42 |
57 | hsa-miR-30b-5p | Down | P = 0.007 | 0.43 |
58 | hsa-let-7b-3p | Down | P = 0.031 | 0.43 |
59 | hsa-miR-23a-3p | Down | P = 0.019 | 0.49 |
Fold change >2 (or <0.5) fold with P ≥ 0.05 | ||||
1 | hsa-miR-141-3p | Down | NS | 0.24 |
2 | hsa-miR-193b-3p | Down | NS | 0.31 |
3 | hsa-miR-485-3p | Down | NS | 0.32 |
4 | hsa-miR-20a-3p | Down | NS | 0.32 |
5 | hsa-miR-154-5p | Down | NS | 0.35 |
6 | hsa-miR-409-3p | Down | NS | 0.40 |
7 | hsa-miR-551b-3p | Down | NS | 0.40 |
8 | hsa-miR-215 | Down | NS | 0.41 |
9 | hsa-miR-95 | Down | NS | 0.42 |
10 | hsa-miR-127-3p | Down | NS | 0.43 |
11 | hsa-miR-185-5p | Down | NS | 0.43 |
12 | hsa-miR-133a | Down | NS | 0.43 |
13 | hsa-miR-1 | Down | NS | 0.45 |
14 | hsa-miR-199a-3p | Down | NS | 0.46 |
15 | hsa-miR-182-5p | Down | NS | 0.47 |
16 | hsa-miR-143-3p | Down | NS | 0.48 |
17 | hsa-miR-192-5p | Down | NS | 0.48 |
18 | hsa-miR-500a-5p | Down | NS | 0.48 |
19 | hsa-miR-590-5p | Down | NS | 0.49 |
20 | hsa-let-7i-3p | Up | NS | 2.20 |
21 | hsa-miR-296-5p | Up | NS | 5.00 |
Student’s t-test.
MicroRNAs were considered differentially expressed at a fold change >1.5.
NS, no significant difference (P ≥ 0.05).