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. 2016 Jan 1;37(8):2780–2794. doi: 10.1177/0271678X16675368

Figure 7.

Figure 7.

Correlation of expression and activation of NKCC1/WNK pathway signaling proteins, infarct volume and hemisphere swelling in ischemic SHR and WKY brains. (a) Correlation between phosphorylation of NKCC1 and expression of WNK kinases at 6 h after MCAO in WKY and SHRs (p < 0.05, Pearson’s correlation). (b) Correlation between phosphorylation of NKCC1 and expression of WNK kinases versus infarct volume (p < 0.05, Pearson’s correlation). (c) Correlation between NKCC1 phosphorylation, and expression of WNK1/2/4 kinases versus hemispheric swelling (p < 0.05, Pearson correlation). These correlation analyses used the same cohort of data from Figures 1–3.