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. Author manuscript; available in PMC: 2017 Jul 31.
Published in final edited form as: Cell Rep. 2017 Jun 20;19(12):2441–2450. doi: 10.1016/j.celrep.2017.05.085

Figure 2. NPF Signaling Regulates the Physiological State of the Fly.

Figure 2

(A–B) Loss of NPF signaling suppresses starvation-induced sleep loss. (A) Sleep profiles of starved and fed control flies carrying the NPFSK2 allele compared to control genotypes. n=14–15. (B) Percent change in 12h dark period sleep during the first day of starvation compared to prior 12h dark fed baseline period. (C) NPF cell activation increases liquid food consumption in adult male flies. n=11 experimental replicates. (D) NPF cell activation decreases whole male adult fly triacylglyceride levels. n=12 experimental replicates. (E) NPF-expressing cell activation renders adult male flies sensitive to starvation. All error bars indicate SEM. See also Figure S2, S3.