Fig. 4.

SOX10 and MIST1 mark subpopulations of acinar cells in developing and adult acini. (A) SOX10 and MIST1 co-staining revealed the subpopulations of acinar cells at P4 and adult stages. Three types of epithelial cells were readily detected in acini, including SOX10⁺MIST1−, SOX10⁺MIST1⁺ and SOX10−MIST1⁺ cells. b,d are magnifications of boxed regions in a,c, respectively. Scale bars: 100 μm in a,c; 25 μm in b,d. (B) Quantification of the epithelial cells expressing SOX10 and MIST1 at P4 (n=3) and adult stages (n=3) (data are mean±s.e.m.).