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. 2017 Jul 24;13:568–580. doi: 10.1016/j.redox.2017.07.013

Fig. 4.

Fig. 4

Reduced chaperone expression in CaNrf2-TG mice. A) Heat map illustrating RNA sequencing log2 expression changes of the top 25 DEG's contained within IPA's biological function of post translational modifications. B) Real-time qPCR validation of 4 genes within the post translational modifications category. Heat map illustrating RNA sequencing log2 expression changes of the top 25 DEG's contained within IPA's biological function of cellular compromise. Real-time qPCR validation of 4 genes within the cellular compromise category. In panels B & D, the expression levels of genes were normalized to Gapdh and/or Arbp1/Rplp0 house-keeping genes. *p < 0.05, **p < 0.01, ***p < 0.001.