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Disruption of lung development in Sin3af/f mutant mice is only partially mediated by apoptosis. (A) Representative immunofluorescence staining of E12.5 embryonic lungs from Sin3af/f mutant and Sin3af/+ littermates showing cleaved caspase 3 (cCasp3) and E-cadherin. (B) Whole-mount images of E11.5 lung explant cultures supplemented with the caspase inhibitor Z-VAD-FMK or vehicle (DMSO) control.
