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. 2017 May 22;18(6):379–391. doi: 10.1080/15384047.2017.1323586

Table 1.

Name and the chemical structures of CtBP inhibitors.

Name of the compound Structure of compound Mode of action
MTOB graphic file with name kcbt-18-06-1323586-i001.gif Substrate at low concentrations, but dehydrogenase inhibitor at high concentrations.86,88
2-Keto-4-(methylthio)butyric acid
HIPP derivatives graphic file with name kcbt-18-06-1323586-i003.gif Dehydrogenase inhibitors.82,89
(2-Hydroxyimino-3-phenyl-propionic acid)
Cyclic Peptide CP61 graphic file with name kcbt-18-06-1323586-i005.gif Inhibitor of homo/ hetero-dimerization of CtBP1 and CtBP2.92
(cyclo-SGWTVVRMY)
NSC95397 graphic file with name kcbt-18-06-1323586-i007.gif Inhibitor of CtBP interaction with partners such as E1A that contain PxDLS sequences.93