TABLE I.
Alignment of Region II-plus Motifs from TSP, CS, and TRAP
| Protein | Sequencea |
|---|---|
| Thrombospondin | PWSSCSVTCGDGVITRIR |
| P. falciparum CS Protein | EWSPCSVTCGNGIQVRIK |
| P. yoelii CS Protein | EWSQCSVTCGSGVRVRKR |
| P. falciparum TRAP | EWSPCSVTCGKGTRSRKR |
a
The conserved tryptophan is underlined, CSVTCG is shown in boldface, and the downstream basic and hydrophobic residues are in italics. The amino acid sequences derive from the following sources: TSP (Lawler and Hynes 1986), P. falciparum CS (Dame et al. 1984), P. yoelii CS (Lal et al. 1987), and P. falciparum TRAP (Robson et al. 1988).