Table 2.
Univariate analysis of the DFS and OS of MBC and TNBC
| Characteristic | Patients (n) | 5-year DFS (%) | P-value | 5-year OS (%) | P-value | |
|---|---|---|---|---|---|---|
| Age | <50 | 169(31.4)* | 86.1 | 0.272 | 82.7 | 0.261 |
| ≥50 | 370(68.6) | 89.9 | 86.4 | |||
| Race | African American | 99(18.4) | 88.7 | 0.628 | 84.9 | 0.855 |
| Others | 11(2.0) | 90.9 | 78.8 | |||
| Caucasian | 429(79.6) | 88.7 | 85.4 | |||
| Histologic Type | MBC | 40(7.4) | 73.7 | <0.001 | 65.3 | 0.002 |
| TNBC | 499(92.6) | 89.9 | 86.6 | |||
| T-Stage | 1 | 324(60.1) | 94.6 | <0.001 | 90.4 | <0.001 |
| 2 | 174(32.3) | 84 | 80.4 | |||
| 3 | 36(6.7) | 65.4 | 69 | |||
| 4 | 5(0.9) | 40 | 40 | |||
| N-Stage | Negative | 365(67.8) | 93.5 | <0.001 | 91.6 | <0.001 |
| Positive | 173(32.2) | 78.9 | 73.1 | |||
| Pathology-Stage | I | 249(46.2) | 97.5 | <0.001 | 94.2 | <0.001 |
| II | 221(41.0) | 86 | 82.4 | |||
| III | 69(12.8) | 66.4 | 62.8 | |||
| Nottingham Grade | 1 | 5(0.9) | 100 | 0.417 | 100 | 0.689 |
| 2 | 46(8.5) | 93.3 | 90 | |||
| 3 | 488(90.5) | 88.2 | 84.5 | |||
| Surgery | Lumpectomy | 360(66.8) | 93.7 | <0.001 | 89.6 | <0.001 |
| Mastectomy | 179(33.2) | 78.6 | 76.1 | |||
| Neoadjuvant | No | 462(85.7) | 92.1 | <0.001 | 88.8 | <0.001 |
| Yes | 77(14.3) | 68.5 | 64.5 | |||
| Radiation Therapy | No | 113(21.2) | 83.3 | 0.108 | 79.9 | 0.044 |
| Yes | 421(78.8) | 90.1 | 86.5 | |||
| Chemotherapy | No | 122(22.7) | 92.1 | 0.177 | 89.8 | 0.151 |
| Yes | 415(77.3) | 87.7 | 84 |
*
N(%);
MBC Metaplastic breast cancer, TNBC Triple negative breast cancer; DFS, disease free survival; OS, overall survival