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IC50 values for pan-PIM inhibitors as determined by PIM enzyme assays.
| PIM inhibitors | PIM1 IC50 (nM) | PIM2 IC50 (nM) | PIM3 IC50 (nM) | Manufacturer |
|---|---|---|---|---|
| SGI-1776 | 7 | 363 | 69 | SuperGen |
| JP11413 | 38 | 0.6 | 9 | Jasco |
| JP11416 | 36 | 1 | 6 | Jasco |
| JP11644 | 32 | 0.7 | 6 | Jasco |
| JP11646 | 24 | 0.5 | 1 | Jasco |
| JP11660 | 42 | 2 | 4 | Jasco |
| JP11662 | 50 | 9 | 4 | Jasco |
